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mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.
Elkabets M, Vora S, Juric D, Morse N, Mino-Kenudson M, Muranen T, Tao J, Campos AB, Rodon J, Ibrahim YH, Serra V, Rodrik-Outmezguine V, Hazra S, Singh S, Kim P, Quadt C, Liu M, Huang A, Rosen N, Engelman JA, Scaltriti M, Baselga J. Elkabets M, et al. Among authors: vora s. Sci Transl Med. 2013 Jul 31;5(196):196ra99. doi: 10.1126/scitranslmed.3005747. Sci Transl Med. 2013. PMID: 23903756 Free PMC article.
CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors.
Vora SR, Juric D, Kim N, Mino-Kenudson M, Huynh T, Costa C, Lockerman EL, Pollack SF, Liu M, Li X, Lehar J, Wiesmann M, Wartmann M, Chen Y, Cao ZA, Pinzon-Ortiz M, Kim S, Schlegel R, Huang A, Engelman JA. Vora SR, et al. Cancer Cell. 2014 Jul 14;26(1):136-49. doi: 10.1016/j.ccr.2014.05.020. Epub 2014 Jul 4. Cancer Cell. 2014. PMID: 25002028 Free PMC article. Clinical Trial.
Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cells.
Vora S, Chatterjee S, Andrew A, Kumar RP, Proctor M, Zeng Z, Bhatt R, Nazareth D, Fernando M, Jones MJK, He Y, Hooper JD, McMillan NAJ, Urosevic J, Saeh J, Travers J, Cimini D, Chen J, Gabrielli B. Vora S, et al. Cell Death Dis. 2025 Jan 8;16(1):7. doi: 10.1038/s41419-024-07329-7. Cell Death Dis. 2025. PMID: 39779678 Free PMC article.
Five-Year Outcomes of Moderately Hypofractionated Proton Therapy Incorporating Elective Pelvic Nodal Irradiation for High-Risk Prostate Cancer.
Choo R, Hillman DW, Mitchell C, Daniels T, Vargas C, Rwigema JC, Corbin K, Keole S, Vora S, Merrell K, Stish B, Pisansky TM, Davis BJ, Amundson A, Wong W. Choo R, et al. Among authors: vora s. Int J Radiat Oncol Biol Phys. 2024 Dec 11:S0360-3016(24)03722-2. doi: 10.1016/j.ijrobp.2024.11.115. Online ahead of print. Int J Radiat Oncol Biol Phys. 2024. PMID: 39672515
The Global Kidney Patient Trials Network and the CAPTIVATE Platform Clinical Trial Design: A Trial Protocol.
Kotwal SS, Perkovic V, Jardine MJ, Kim D, Shah NA, Lin E, Coggan S, Billot L, Vart P, Wheeler DC, de Boer IH, Zhang H, Hou FF, Sugawara Y, Marion J, Lewis RJ, Berry LR, McGlothlin A, Jha V, De Nicola L, Gorriz JL, Heerspink HJL; GKPTN and CAPTIVATE Investigators. Kotwal SS, et al. JAMA Netw Open. 2024 Dec 2;7(12):e2449998. doi: 10.1001/jamanetworkopen.2024.49998. JAMA Netw Open. 2024. PMID: 39661388 Free PMC article.
Characterizing the role of left ventricular indices and biventricular interaction in bronchopulmonary dysplasia-associated pulmonary hypertension in extreme prematurity.
Gopagondanahalli KR, Sundararaghavan S, Tan TH, Yeo KT, Vora SJ, Ng WD, Choo JTL, Ang WL, Binte Mohamad Taib NQ, Han Ying NW, Rajadurai VS, Abdul Haium AA. Gopagondanahalli KR, et al. Among authors: vora sj. Neonatology. 2024 Dec 4:1-17. doi: 10.1159/000542980. Online ahead of print. Neonatology. 2024. PMID: 39631380
424 results