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Page 1
Enzymatic Cascades for Stereoselective and Regioselective Amide Bond Assembly.
Torri D, Bering L, Yates LRL, Angiolini SM, Xu G, Cuesta-Hoyos S, Shepherd SA, Micklefield J. Torri D, et al. Among authors: shepherd sa. Angew Chem Int Ed Engl. 2025 Jan 10:e202422185. doi: 10.1002/anie.202422185. Online ahead of print. Angew Chem Int Ed Engl. 2025. PMID: 39792621
Cryptic enzymatic assembly of peptides armed with β-lactone warheads.
Xu G, Torri D, Cuesta-Hoyos S, Panda D, Yates LRL, Zallot R, Bian K, Jia D, Iorgu AI, Levy C, Shepherd SA, Micklefield J. Xu G, et al. Among authors: shepherd sa. Nat Chem Biol. 2024 Oct;20(10):1371-1379. doi: 10.1038/s41589-024-01657-7. Epub 2024 Jul 1. Nat Chem Biol. 2024. PMID: 38951647 Free PMC article.
Merging enzymes with chemocatalysis for amide bond synthesis.
Bering L, Craven EJ, Sowerby Thomas SA, Shepherd SA, Micklefield J. Bering L, et al. Among authors: shepherd sa. Nat Commun. 2022 Jan 19;13(1):380. doi: 10.1038/s41467-022-28005-4. Nat Commun. 2022. PMID: 35046426 Free PMC article.
Hyponatremia in the Neurologically Ill Patient: A Review.
Lerner DP, Shepherd SA, Batra A. Lerner DP, et al. Among authors: shepherd sa. Neurohospitalist. 2020 Jul;10(3):208-216. doi: 10.1177/1941874419895124. Epub 2020 Jan 10. Neurohospitalist. 2020. PMID: 32549945 Free PMC article. Review.
Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase.
Bennett MR, Thompson ML, Shepherd SA, Dunstan MS, Herbert AJ, Smith DRM, Cronin VA, Menon BRK, Levy C, Micklefield J. Bennett MR, et al. Among authors: shepherd sa. Angew Chem Int Ed Engl. 2018 Aug 13;57(33):10600-10604. doi: 10.1002/anie.201805060. Epub 2018 Jun 28. Angew Chem Int Ed Engl. 2018. PMID: 29791083 Free PMC article.
RadH: A Versatile Halogenase for Integration into Synthetic Pathways.
Menon BRK, Brandenburger E, Sharif HH, Klemstein U, Shepherd SA, Greaney MF, Micklefield J. Menon BRK, et al. Among authors: shepherd sa. Angew Chem Int Ed Engl. 2017 Sep 18;56(39):11841-11845. doi: 10.1002/anie.201706342. Epub 2017 Aug 18. Angew Chem Int Ed Engl. 2017. PMID: 28722773 Free PMC article.
Development of Halogenase Enzymes for Use in Synthesis.
Latham J, Brandenburger E, Shepherd SA, Menon BRK, Micklefield J. Latham J, et al. Among authors: shepherd sa. Chem Rev. 2018 Jan 10;118(1):232-269. doi: 10.1021/acs.chemrev.7b00032. Epub 2017 May 3. Chem Rev. 2018. PMID: 28466644 Review.
Recent advances in methyltransferase biocatalysis.
Bennett MR, Shepherd SA, Cronin VA, Micklefield J. Bennett MR, et al. Among authors: shepherd sa. Curr Opin Chem Biol. 2017 Apr;37:97-106. doi: 10.1016/j.cbpa.2017.01.020. Epub 2017 Mar 2. Curr Opin Chem Biol. 2017. PMID: 28259085 Review.
22 results