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Page 1
Chronic metabotropic glutamate receptor 5 inhibition corrects local alterations of brain activity and improves cognitive performance in fragile X mice.
Michalon A, Bruns A, Risterucci C, Honer M, Ballard TM, Ozmen L, Jaeschke G, Wettstein JG, von Kienlin M, Künnecke B, Lindemann L. Michalon A, et al. Among authors: ballard tm. Biol Psychiatry. 2014 Feb 1;75(3):189-97. doi: 10.1016/j.biopsych.2013.05.038. Epub 2013 Jul 30. Biol Psychiatry. 2014. PMID: 23910948
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Michalon A, Sidorov M, Ballard TM, Ozmen L, Spooren W, Wettstein JG, Jaeschke G, Bear MF, Lindemann L. Michalon A, et al. Among authors: ballard tm. Neuron. 2012 Apr 12;74(1):49-56. doi: 10.1016/j.neuron.2012.03.009. Neuron. 2012. PMID: 22500629 Free PMC article.
Cognitive performance in neurokinin 3 receptor knockout mice.
Nordquist RE, Delenclos M, Ballard TM, Savignac H, Pauly-Evers M, Ozmen L, Spooren W. Nordquist RE, et al. Among authors: ballard tm. Psychopharmacology (Berl). 2008 Jun;198(2):211-20. doi: 10.1007/s00213-008-1119-6. Epub 2008 Mar 20. Psychopharmacology (Berl). 2008. PMID: 18351324
Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists.
Jaeschke G, Porter R, Büttelmann B, Ceccarelli SM, Guba W, Kuhn B, Kolczewski S, Huwyler J, Mutel V, Peters JU, Ballard T, Prinssen E, Vieira E, Wichmann J, Spooren W. Jaeschke G, et al. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1307-11. doi: 10.1016/j.bmcl.2006.12.033. Epub 2006 Dec 15. Bioorg Med Chem Lett. 2007. PMID: 17196387
Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.
Porter RH, Jaeschke G, Spooren W, Ballard TM, Büttelmann B, Kolczewski S, Peters JU, Prinssen E, Wichmann J, Vieira E, Mühlemann A, Gatti S, Mutel V, Malherbe P. Porter RH, et al. Among authors: ballard tm. J Pharmacol Exp Ther. 2005 Nov;315(2):711-21. doi: 10.1124/jpet.105.089839. Epub 2005 Jul 22. J Pharmacol Exp Ther. 2005. PMID: 16040814
RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors.
Ballard TM, Knoflach F, Prinssen E, Borroni E, Vivian JA, Basile J, Gasser R, Moreau JL, Wettstein JG, Buettelmann B, Knust H, Thomas AW, Trube G, Hernandez MC. Ballard TM, et al. Psychopharmacology (Berl). 2009 Jan;202(1-3):207-23. doi: 10.1007/s00213-008-1357-7. Epub 2008 Oct 21. Psychopharmacology (Berl). 2009. PMID: 18936916
Pharmacological characterization of senktide-induced tail whips.
Nordquist RE, Ballard TM, Algeyer B, Pauly-Evers M, Ozmen L, Spooren W. Nordquist RE, et al. Among authors: ballard tm. Neuropharmacology. 2010 Jan;58(1):259-67. doi: 10.1016/j.neuropharm.2009.04.018. Epub 2009 Jun 21. Neuropharmacology. 2010. PMID: 19540857
Drug targets for cognitive enhancement in neuropsychiatric disorders.
Wallace TL, Ballard TM, Pouzet B, Riedel WJ, Wettstein JG. Wallace TL, et al. Among authors: ballard tm. Pharmacol Biochem Behav. 2011 Aug;99(2):130-45. doi: 10.1016/j.pbb.2011.03.022. Epub 2011 Apr 1. Pharmacol Biochem Behav. 2011. PMID: 21463652 Review.
56 results