Syam YM - Search Results

1

A novel class of substituted spiro [quinazoline-2,1'-cyclohexane] derivatives as effective PPAR-1 inhibitors: molecular modeling, synthesis, cytotoxic and enzyme assay evaluation.

Amin KM, Anwar MM, Syam YM, Khedr MA, Kamel MM, Kassem EM. Amin KM, et al. Among authors: syam ym. Acta Pol Pharm. 2013 Jul-Aug;70(4):687-708. Acta Pol Pharm. 2013. PMID: 23923393 Free article.

2

Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1'- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents.

Amin KM, Kamel MM, Anwar MM, Khedr M, Syam YM. Amin KM, et al. Among authors: syam ym. Eur J Med Chem. 2010 Jun;45(6):2117-31. doi: 10.1016/j.ejmech.2009.12.078. Epub 2010 Jan 21. Eur J Med Chem. 2010. PMID: 20137837

3

Synthesis, cytotoxic evaluation and molecular docking study of novel quinazoline derivatives as PARP-1 inhibitors.

Amin KM, Anwar MM, Kamel MM, Kassem EM, Syam YM, Elseginy SA. Amin KM, et al. Among authors: syam ym. Acta Pol Pharm. 2013 Sep-Oct;70(5):833-49. Acta Pol Pharm. 2013. PMID: 24147361 Free article.

4

Synthesis and molecular docking studies of new furochromone derivatives as p38α MAPK inhibitors targeting human breast cancer MCF-7 cells.

Amin KM, Syam YM, Anwar MM, Ali HI, Abdel-Ghani TM, Serry AM. Amin KM, et al. Among authors: syam ym. Bioorg Med Chem. 2017 Apr 15;25(8):2423-2436. doi: 10.1016/j.bmc.2017.02.065. Epub 2017 Mar 3. Bioorg Med Chem. 2017. PMID: 28291685

5

Design, Synthesis and Biological Evaluation of Spiro Cyclohexane-1,2- Quinazoline Derivatives as Potent Dipeptidyl Peptidase IV Inhibitors.

Syam YM, El-Karim SSA, Nasr T, Elseginy SA, Anwar MM, Kamel MM, Ali HF. Syam YM, et al. Mini Rev Med Chem. 2019;19(3):250-269. doi: 10.2174/1389557517666170828121018. Mini Rev Med Chem. 2019. PMID: 28847268

6

Synthesis and molecular docking study of new benzofuran and furo[3,2-g]chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors.

Amin KM, Syam YM, Anwar MM, Ali HI, Abdel-Ghani TM, Serry AM. Amin KM, et al. Among authors: syam ym. Bioorg Chem. 2018 Feb;76:487-500. doi: 10.1016/j.bioorg.2017.12.029. Epub 2018 Jan 2. Bioorg Chem. 2018. PMID: 29310080

7

Development of Promising Thiopyrimidine-Based Anti-cancer and Antimicrobial Agents: Synthesis and QSAR Analysis.

Syam YM, Anwar MM, Kotb ER, Elseginy SA, Awad HM, Awad GEA. Syam YM, et al. Mini Rev Med Chem. 2019;19(15):1255-1275. doi: 10.2174/1389557518666180330110828. Mini Rev Med Chem. 2019. PMID: 29600761

8

Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution studies.

Abd El-Karim SS, Anwar MM, Syam YM, Nael MA, Ali HF, Motaleb MA. Abd El-Karim SS, et al. Among authors: syam ym. Bioorg Chem. 2018 Dec;81:481-493. doi: 10.1016/j.bioorg.2018.09.021. Epub 2018 Sep 12. Bioorg Chem. 2018. PMID: 30243239

9

New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies.

Abd El-Karim SS, Syam YM, El Kerdawy AM, Abdelghany TM. Abd El-Karim SS, et al. Among authors: syam ym. Bioorg Chem. 2019 May;86:80-96. doi: 10.1016/j.bioorg.2019.01.026. Epub 2019 Jan 19. Bioorg Chem. 2019. PMID: 30685646

10

New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies.

Syam YM, Anwar MM, Abd El-Karim SS, Elseginy SA, Essa BM, Sakr TM. Syam YM, et al. RSC Adv. 2021 Nov 17;11(58):36989-37010. doi: 10.1039/d1ra06799k. eCollection 2021 Nov 10. RSC Adv. 2021. PMID: 35494381 Free PMC article.

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