Lippard SJ - Search Results

1

Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis.

Kellinger MW, Park GY, Chong J, Lippard SJ, Wang D. Kellinger MW, et al. Among authors: lippard sj. J Am Chem Soc. 2013 Sep 4;135(35):13054-61. doi: 10.1021/ja405475y. Epub 2013 Aug 25. J Am Chem Soc. 2013. PMID: 23927577 Free PMC article.

2

Phenanthriplatin Acts As a Covalent Poison of Topoisomerase II Cleavage Complexes.

Riddell IA, Agama K, Park GY, Pommier Y, Lippard SJ. Riddell IA, et al. Among authors: lippard sj. ACS Chem Biol. 2016 Nov 18;11(11):2996-3001. doi: 10.1021/acschembio.6b00565. Epub 2016 Oct 6. ACS Chem Biol. 2016. PMID: 27648475 Free PMC article.

3

X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.

Wang D, Zhu G, Huang X, Lippard SJ. Wang D, et al. Among authors: lippard sj. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9584-9. doi: 10.1073/pnas.1002565107. Epub 2010 May 6. Proc Natl Acad Sci U S A. 2010. PMID: 20448203 Free PMC article.

4

Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile.

Park GY, Wilson JJ, Song Y, Lippard SJ. Park GY, et al. Among authors: lippard sj. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11987-92. doi: 10.1073/pnas.1207670109. Epub 2012 Jul 6. Proc Natl Acad Sci U S A. 2012. PMID: 22773807 Free PMC article.

5

Understanding and improving platinum anticancer drugs--phenanthriplatin.

Johnstone TC, Park GY, Lippard SJ. Johnstone TC, et al. Among authors: lippard sj. Anticancer Res. 2014 Jan;34(1):471-6. Anticancer Res. 2014. PMID: 24403503 Free PMC article. Review.

6

Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage.

Gregory MT, Park GY, Johnstone TC, Lee YS, Yang W, Lippard SJ. Gregory MT, et al. Among authors: lippard sj. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9133-8. doi: 10.1073/pnas.1405739111. Epub 2014 Jun 9. Proc Natl Acad Sci U S A. 2014. PMID: 24927576 Free PMC article.

7

Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin.

Riddell IA, Johnstone TC, Park GY, Lippard SJ. Riddell IA, et al. Among authors: lippard sj. Chemistry. 2016 May 23;22(22):7574-81. doi: 10.1002/chem.201600236. Epub 2016 Apr 25. Chemistry. 2016. PMID: 27111128 Free PMC article.

8

Effects of monofunctional platinum agents on bacterial growth: a retrospective study.

Johnstone TC, Alexander SM, Lin W, Lippard SJ. Johnstone TC, et al. Among authors: lippard sj. J Am Chem Soc. 2014 Jan 8;136(1):116-8. doi: 10.1021/ja411742c. Epub 2013 Dec 23. J Am Chem Soc. 2014. PMID: 24364388 Free PMC article.

9

The chiral potential of phenanthriplatin and its influence on guanine binding.

Johnstone TC, Lippard SJ. Johnstone TC, et al. Among authors: lippard sj. J Am Chem Soc. 2014 Feb 5;136(5):2126-34. doi: 10.1021/ja4125115. Epub 2014 Jan 27. J Am Chem Soc. 2014. PMID: 24417436 Free PMC article.

10

Cellular processing of platinum anticancer drugs.

Wang D, Lippard SJ. Wang D, et al. Among authors: lippard sj. Nat Rev Drug Discov. 2005 Apr;4(4):307-20. doi: 10.1038/nrd1691. Nat Rev Drug Discov. 2005. PMID: 15789122 Review.

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