Plun-Favreau H - Search Results

1

The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy.

Burchell VS, Nelson DE, Sanchez-Martinez A, Delgado-Camprubi M, Ivatt RM, Pogson JH, Randle SJ, Wray S, Lewis PA, Houlden H, Abramov AY, Hardy J, Wood NW, Whitworth AJ, Laman H, Plun-Favreau H. Burchell VS, et al. Nat Neurosci. 2013 Sep;16(9):1257-65. doi: 10.1038/nn.3489. Epub 2013 Aug 11. Nat Neurosci. 2013. PMID: 23933751 Free PMC article.

2

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

Plun-Favreau H, Klupsch K, Moisoi N, Gandhi S, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N, Wood NW, Martins LM, Downward J. Plun-Favreau H, et al. Nat Cell Biol. 2007 Nov;9(11):1243-52. doi: 10.1038/ncb1644. Epub 2007 Sep 30. Nat Cell Biol. 2007. PMID: 17906618

3

Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway?

Fitzgerald JC, Plun-Favreau H. Fitzgerald JC, et al. FEBS J. 2008 Dec;275(23):5758-66. doi: 10.1111/j.1742-4658.2008.06708.x. FEBS J. 2008. PMID: 19021753 Free article. Review.

4

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response.

Moisoi N, Klupsch K, Fedele V, East P, Sharma S, Renton A, Plun-Favreau H, Edwards RE, Teismann P, Esposti MD, Morrison AD, Wood NW, Downward J, Martins LM. Moisoi N, et al. Cell Death Differ. 2009 Mar;16(3):449-64. doi: 10.1038/cdd.2008.166. Epub 2008 Nov 21. Cell Death Differ. 2009. PMID: 19023330

5

What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?

Plun-Favreau H, Gandhi S, Wood-Kaczmar A, Deas E, Yao Z, Wood NW. Plun-Favreau H, et al. Ann N Y Acad Sci. 2008 Dec;1147:30-6. doi: 10.1196/annals.1427.032. Ann N Y Acad Sci. 2008. PMID: 19076428

6

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin.

Tain LS, Chowdhury RB, Tao RN, Plun-Favreau H, Moisoi N, Martins LM, Downward J, Whitworth AJ, Tapon N. Tain LS, et al. Cell Death Differ. 2009 Aug;16(8):1118-25. doi: 10.1038/cdd.2009.23. Epub 2009 Mar 13. Cell Death Differ. 2009. PMID: 19282869 Free PMC article.

7

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.

Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. Gandhi S, et al. Mol Cell. 2009 Mar 13;33(5):627-38. doi: 10.1016/j.molcel.2009.02.013. Mol Cell. 2009. PMID: 19285945 Free PMC article.

8

PINK1 function in health and disease.

Deas E, Plun-Favreau H, Wood NW. Deas E, et al. EMBO Mol Med. 2009 Jun;1(3):152-65. doi: 10.1002/emmm.200900024. EMBO Mol Med. 2009. PMID: 20049715 Free PMC article. Review.

9

Targeting mitochondrial dysfunction in neurodegenerative disease: Part I.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Expert Opin Ther Targets. 2010 Apr;14(4):369-85. doi: 10.1517/14728221003652489. Expert Opin Ther Targets. 2010. PMID: 20184395 Review.

10

Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Expert Opin Ther Targets. 2010 May;14(5):497-511. doi: 10.1517/14728221003730434. Expert Opin Ther Targets. 2010. PMID: 20334487 Review.

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