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The combination of four different clinical decision rules and an age-adjusted D-dimer cut-off increases the number of patients in whom acute pulmonary embolism can safely be excluded.
van Es J, Mos I, Douma R, Erkens P, Durian M, Nizet T, van Houten A, Hofstee H, ten Cate H, Ullmann E, Büller H, Huisman M, Kamphuisen PW. van Es J, et al. Thromb Haemost. 2012 Jan;107(1):167-71. doi: 10.1160/TH11-08-0587. Epub 2011 Nov 10. Thromb Haemost. 2012. PMID: 22072293
Accuracy of clinical decision rule, D-dimer and spiral computed tomography in patients with malignancy, previous venous thromboembolism, COPD or heart failure and in older patients with suspected pulmonary embolism.
Sohne M, Kruip MJ, Nijkeuter M, Tick L, Kwakkel H, Halkes SJ, Huisman MV, Buller HR; Christoper Study Group. Sohne M, et al. Among authors: buller hr. J Thromb Haemost. 2006 May;4(5):1042-6. doi: 10.1111/j.1538-7836.2006.01918.x. J Thromb Haemost. 2006. PMID: 16689757 Free article.
High D-dimer level is associated with increased 15-d and 3 months mortality through a more central localization of pulmonary emboli and serious comorbidity.
Klok FA, Djurabi RK, Nijkeuter M, Eikenboom HC, Leebeek FW, Kramer MH, Kaasjager K, Kamphuisen PW, Büller HR, Huisman MV. Klok FA, et al. Among authors: buller hr. Br J Haematol. 2008 Jan;140(2):218-22. doi: 10.1111/j.1365-2141.2007.06888.x. Epub 2007 Nov 19. Br J Haematol. 2008. PMID: 18028485 Free article.
High D-dimer levels increase the likelihood of pulmonary embolism.
Tick LW, Nijkeuter M, Kramer MH, Hovens MM, Büller HR, Leebeek FW, Huisman MV; Christopher Study Investigators. Tick LW, et al. Among authors: buller hr. J Intern Med. 2008 Aug;264(2):195-200. doi: 10.1111/j.1365-2796.2008.01972.x. Epub 2008 Apr 29. J Intern Med. 2008. PMID: 18452520 Free article.
PO-07 - Excluding pulmonary embolism in cancer patients using the Wells rule and age-adjusted D-dimer testing: an individual patient data meta-analysis.
van Es N, van der Hulle T, van Es J, den Exter PL, Douma RA, Goekoop RJ, Mos IC, Garcia JG, Kamphuisen PW, Huisman MV, Klok FA, Büller HR, Bossuyt PM. van Es N, et al. Among authors: buller hr. Thromb Res. 2016 Apr;140 Suppl 1:S179. doi: 10.1016/S0049-3848(16)30140-2. Epub 2016 Apr 8. Thromb Res. 2016. PMID: 27161697
736 results