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Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail.
Pettitt J, Zeitlin L, Kim DH, Working C, Johnson JC, Bohorov O, Bratcher B, Hiatt E, Hume SD, Johnson AK, Morton J, Pauly MH, Whaley KJ, Ingram MF, Zovanyi A, Heinrich M, Piper A, Zelko J, Olinger GG. Pettitt J, et al. Among authors: hiatt e. Sci Transl Med. 2013 Aug 21;5(199):199ra113. doi: 10.1126/scitranslmed.3006608. Sci Transl Med. 2013. PMID: 23966302
Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques.
Olinger GG Jr, Pettitt J, Kim D, Working C, Bohorov O, Bratcher B, Hiatt E, Hume SD, Johnson AK, Morton J, Pauly M, Whaley KJ, Lear CM, Biggins JE, Scully C, Hensley L, Zeitlin L. Olinger GG Jr, et al. Among authors: hiatt e. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18030-5. doi: 10.1073/pnas.1213709109. Epub 2012 Oct 15. Proc Natl Acad Sci U S A. 2012. PMID: 23071322 Free PMC article.
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp.
Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP. Qiu X, et al. Among authors: hiatt e. Nature. 2014 Oct 2;514(7520):47-53. doi: 10.1038/nature13777. Epub 2014 Aug 29. Nature. 2014. PMID: 25171469 Free PMC article.
Chimeric plantibody passively protects mice against aerosolized ricin challenge.
Sully EK, Whaley KJ, Bohorova N, Bohorov O, Goodman C, Kim DH, Pauly MH, Velasco J, Hiatt E, Morton J, Swope K, Roy CJ, Zeitlin L, Mantis NJ. Sully EK, et al. Among authors: hiatt e. Clin Vaccine Immunol. 2014 May;21(5):777-82. doi: 10.1128/CVI.00003-14. Epub 2014 Feb 26. Clin Vaccine Immunol. 2014. PMID: 24574537 Free PMC article.
Emerging antibody-based products.
Whaley KJ, Morton J, Hume S, Hiatt E, Bratcher B, Klimyuk V, Hiatt A, Pauly M, Zeitlin L. Whaley KJ, et al. Among authors: hiatt a, hiatt e. Curr Top Microbiol Immunol. 2014;375:107-26. doi: 10.1007/82_2012_240. Curr Top Microbiol Immunol. 2014. PMID: 22772797 Review.
Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems.
Pogue GP, Vojdani F, Palmer KE, Hiatt E, Hume S, Phelps J, Long L, Bohorova N, Kim D, Pauly M, Velasco J, Whaley K, Zeitlin L, Garger SJ, White E, Bai Y, Haydon H, Bratcher B. Pogue GP, et al. Among authors: hiatt e. Plant Biotechnol J. 2010 Jun;8(5):638-54. doi: 10.1111/j.1467-7652.2009.00495.x. Plant Biotechnol J. 2010. PMID: 20514694 Free article. Review.
67 results