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Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia.
Lashinger LM, Malone LM, McArthur MJ, Goldberg JA, Daniels EA, Pavone A, Colby JK, Smith NC, Perkins SN, Fischer SM, Hursting SD. Lashinger LM, et al. Among authors: fischer sm. Cancer Prev Res (Phila). 2011 Jul;4(7):1030-40. doi: 10.1158/1940-6207.CAPR-11-0027. Epub 2011 May 18. Cancer Prev Res (Phila). 2011. PMID: 21593196 Free PMC article.
Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner.
Harvey AE, Lashinger LM, Hays D, Harrison LM, Lewis K, Fischer SM, Hursting SD. Harvey AE, et al. Among authors: fischer sm. PLoS One. 2014 May 7;9(5):e94151. doi: 10.1371/journal.pone.0094151. eCollection 2014. PLoS One. 2014. PMID: 24804677 Free PMC article.
362 results