Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1+CD8+ T cells.
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Zhang Z, et al. Among authors: hofmann m.
Nat Immunol. 2024 Dec 19. doi: 10.1038/s41590-024-02027-0. Online ahead of print.
Nat Immunol. 2024.
PMID: 39702858