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Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway.
Parra V, Verdejo HE, Iglewski M, Del Campo A, Troncoso R, Jones D, Zhu Y, Kuzmicic J, Pennanen C, Lopez-Crisosto C, Jaña F, Ferreira J, Noguera E, Chiong M, Bernlohr DA, Klip A, Hill JA, Rothermel BA, Abel ED, Zorzano A, Lavandero S. Parra V, et al. Among authors: abel ed. Diabetes. 2014 Jan;63(1):75-88. doi: 10.2337/db13-0340. Epub 2013 Sep 5. Diabetes. 2014. PMID: 24009260 Free PMC article.
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy.
Troncoso R, Vicencio JM, Parra V, Nemchenko A, Kawashima Y, Del Campo A, Toro B, Battiprolu PK, Aranguiz P, Chiong M, Yakar S, Gillette TG, Hill JA, Abel ED, Leroith D, Lavandero S. Troncoso R, et al. Among authors: abel ed. Cardiovasc Res. 2012 Feb 1;93(2):320-9. doi: 10.1093/cvr/cvr321. Epub 2011 Dec 1. Cardiovasc Res. 2012. PMID: 22135164 Free PMC article.
Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo.
Bharath LP, Ruan T, Li Y, Ravindran A, Wan X, Nhan JK, Walker ML, Deeter L, Goodrich R, Johnson E, Munday D, Mueller R, Kunz D, Jones D, Reese V, Summers SA, Babu PV, Holland WL, Zhang QJ, Abel ED, Symons JD. Bharath LP, et al. Among authors: abel ed. Diabetes. 2015 Nov;64(11):3914-26. doi: 10.2337/db15-0244. Epub 2015 Aug 7. Diabetes. 2015. PMID: 26253611 Free PMC article.
Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction.
Wende AR, Schell JC, Ha CM, Pepin ME, Khalimonchuk O, Schwertz H, Pereira RO, Brahma MK, Tuinei J, Contreras-Ferrat A, Wang L, Andrizzi CA, Olsen CD, Bradley WE, Dell'Italia LJ, Dillmann WH, Litwin SE, Abel ED. Wende AR, et al. Among authors: abel ed. Diabetes. 2020 Oct;69(10):2094-2111. doi: 10.2337/db19-1057. Epub 2020 May 4. Diabetes. 2020. PMID: 32366681 Free PMC article.
298 results