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Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway.
Parra V, Verdejo HE, Iglewski M, Del Campo A, Troncoso R, Jones D, Zhu Y, Kuzmicic J, Pennanen C, Lopez-Crisosto C, Jaña F, Ferreira J, Noguera E, Chiong M, Bernlohr DA, Klip A, Hill JA, Rothermel BA, Abel ED, Zorzano A, Lavandero S. Parra V, et al. Among authors: ferreira j. Diabetes. 2014 Jan;63(1):75-88. doi: 10.2337/db13-0340. Epub 2013 Sep 5. Diabetes. 2014. PMID: 24009260 Free PMC article.
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress.
Bravo R, Vicencio JM, Parra V, Troncoso R, Munoz JP, Bui M, Quiroga C, Rodriguez AE, Verdejo HE, Ferreira J, Iglewski M, Chiong M, Simmen T, Zorzano A, Hill JA, Rothermel BA, Szabadkai G, Lavandero S. Bravo R, et al. Among authors: ferreira j. J Cell Sci. 2011 Jul 1;124(Pt 13):2143-52. doi: 10.1242/jcs.080762. Epub 2011 May 31. J Cell Sci. 2011. PMID: 21628424 Free PMC article.
Antiproliferative and uncoupling effects of delocalized, lipophilic, cationic gallic acid derivatives on cancer cell lines. Validation in vivo in singenic mice.
Jara JA, Castro-Castillo V, Saavedra-Olavarría J, Peredo L, Pavanni M, Jaña F, Letelier ME, Parra E, Becker MI, Morello A, Kemmerling U, Maya JD, Ferreira J. Jara JA, et al. Among authors: ferreira j. J Med Chem. 2014 Mar 27;57(6):2440-54. doi: 10.1021/jm500174v. Epub 2014 Mar 17. J Med Chem. 2014. PMID: 24568614
Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation.
Urra FA, Córdova-Delgado M, Lapier M, Orellana-Manzano A, Acevedo-Arévalo L, Pessoa-Mahana H, González-Vivanco JM, Martínez-Cifuentes M, Ramírez-Rodríguez O, Millas-Vargas JP, Weiss-López B, Pavani M, Ferreira J, Araya-Maturana R. Urra FA, et al. Among authors: ferreira j. Toxicol Appl Pharmacol. 2016 Jan 15;291:46-57. doi: 10.1016/j.taap.2015.12.005. Epub 2015 Dec 19. Toxicol Appl Pharmacol. 2016. PMID: 26712467
Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin.
Campos-Estrada C, Liempi A, González-Herrera F, Lapier M, Kemmerling U, Pesce B, Ferreira J, López-Muñoz R, Maya JD. Campos-Estrada C, et al. Among authors: ferreira j. PLoS Negl Trop Dis. 2015 May 15;9(5):e0003770. doi: 10.1371/journal.pntd.0003770. eCollection 2015 May. PLoS Negl Trop Dis. 2015. PMID: 25978361 Free PMC article.
5,149 results