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Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
Burger K, Mühl B, Harasim T, Rohrmoser M, Malamoussi A, Orban M, Kellner M, Gruber-Eber A, Kremmer E, Hölzel M, Eick D. Burger K, et al. Among authors: eick d. J Biol Chem. 2010 Apr 16;285(16):12416-25. doi: 10.1074/jbc.M109.074211. Epub 2010 Feb 16. J Biol Chem. 2010. PMID: 20159984 Free PMC article.
Defects in 18 S or 28 S rRNA processing activate the p53 pathway.
Hölzel M, Orban M, Hochstatter J, Rohrmoser M, Harasim T, Malamoussi A, Kremmer E, Längst G, Eick D. Hölzel M, et al. Among authors: eick d. J Biol Chem. 2010 Feb 26;285(9):6364-70. doi: 10.1074/jbc.M109.054734. Epub 2010 Jan 7. J Biol Chem. 2010. PMID: 20056613 Free PMC article.
144 results