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Vascular endothelial growth factor blockade prevents the beneficial effects of β-blocker therapy on cardiac function, angiogenesis, and remodeling in heart failure.
Rengo G, Cannavo A, Liccardo D, Zincarelli C, de Lucia C, Pagano G, Komici K, Parisi V, Scala O, Agresta A, Rapacciuolo A, Perrone Filardi P, Ferrara N, Koch WJ, Trimarco B, Femminella GD, Leosco D. Rengo G, et al. Among authors: rapacciuolo a. Circ Heart Fail. 2013 Nov;6(6):1259-67. doi: 10.1161/CIRCHEARTFAILURE.113.000329. Epub 2013 Sep 12. Circ Heart Fail. 2013. PMID: 24029661
Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation.
Leosco D, Rengo G, Iaccarino G, Filippelli A, Lymperopoulos A, Zincarelli C, Fortunato F, Golino L, Marchese M, Esposito G, Rapacciuolo A, Rinaldi B, Ferrara N, Koch WJ, Rengo F. Leosco D, et al. Among authors: rapacciuolo a. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1596-603. doi: 10.1152/ajpheart.00308.2007. Epub 2007 Jun 8. Am J Physiol Heart Circ Physiol. 2007. PMID: 17557919 Free article.
β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy.
Cannavo A, Rengo G, Liccardo D, Pagano G, Zincarelli C, De Angelis MC, Puglia R, Di Pietro E, Rabinowitz JE, Barone MV, Cirillo P, Trimarco B, Palmer TM, Ferrara N, Koch WJ, Leosco D, Rapacciuolo A. Cannavo A, et al. Among authors: rapacciuolo a. Circulation. 2013 Oct 8;128(15):1612-22. doi: 10.1161/CIRCULATIONAHA.113.002659. Epub 2013 Aug 22. Circulation. 2013. PMID: 23969695 Free PMC article.
An imbalance between protective and detrimental molecular pathways is associated with right ventricular dysfunction in congenital heart diseases with outflow obstruction.
di Pietro E, De Angelis MC, Esposito F, Maresca G, Agresta A, Cerrone A, De Filippo O, Kilner PJ, Palma G, Galasso G, Leosco D, Vosa C, Trimarco B, Rapacciuolo A. di Pietro E, et al. Among authors: rapacciuolo a. Int J Cardiol. 2014 Apr 1;172(3):e519-21. doi: 10.1016/j.ijcard.2014.01.077. Epub 2014 Jan 24. Int J Cardiol. 2014. PMID: 24534380 No abstract available.
Insulin resistance is associated with impaired cardiac sympathetic innervation in patients with heart failure.
Paolillo S, Rengo G, Pellegrino T, Formisano R, Pagano G, Gargiulo P, Savarese G, Carotenuto R, Petraglia L, Rapacciuolo A, Perrino C, Piscitelli S, Attena E, Del Guercio L, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P. Paolillo S, et al. Among authors: rapacciuolo a. Eur Heart J Cardiovasc Imaging. 2015 Oct;16(10):1148-53. doi: 10.1093/ehjci/jev061. Epub 2015 Apr 5. Eur Heart J Cardiovasc Imaging. 2015. PMID: 25845954
145 results