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The endolysosomal cysteine cathepsins L and K are involved in macrophage-mediated clearance of Staphylococcus aureus and the concomitant cytokine induction.
FASEB J. 2014 Jan;28(1):162-75. doi: 10.1096/fj.13-232272. Epub 2013 Sep 13.
FASEB J. 2014.
PMID: 24036885
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.
Tholen S, Biniossek ML, Gansz M, Ahrens TD, Schlimpert M, Kizhakkedathu JN, Reinheckel T, Schilling O.
Tholen S, et al. Among authors: gansz m.
Cell Mol Life Sci. 2014 Mar;71(5):899-916. doi: 10.1007/s00018-013-1406-1. Epub 2013 Jun 29.
Cell Mol Life Sci. 2014.
PMID: 23811845
Free PMC article.
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Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.
Tholen S, Biniossek ML, Gansz M, Gomez-Auli A, Bengsch F, Noel A, Kizhakkedathu JN, Boerries M, Busch H, Reinheckel T, Schilling O.
Tholen S, et al. Among authors: gansz m.
Mol Cell Proteomics. 2013 Mar;12(3):611-25. doi: 10.1074/mcp.M112.017962. Epub 2012 Dec 10.
Mol Cell Proteomics. 2013.
PMID: 23233448
Free PMC article.
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