Suen JY - Search Results

1

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

Seow V, Lim J, Iyer A, Suen JY, Ariffin JK, Hohenhaus DM, Sweet MJ, Fairlie DP. Seow V, et al. Among authors: suen jy. J Immunol. 2013 Oct 15;191(8):4308-16. doi: 10.4049/jimmunol.1301355. Epub 2013 Sep 16. J Immunol. 2013. PMID: 24043889

2

A refined agonist pharmacophore for protease activated receptor 2.

Barry GD, Suen JY, Low HB, Pfeiffer B, Flanagan B, Halili M, Le GT, Fairlie DP. Barry GD, et al. Among authors: suen jy. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5552-7. doi: 10.1016/j.bmcl.2007.08.026. Epub 2007 Aug 16. Bioorg Med Chem Lett. 2007. PMID: 17765542

3

Novel agonists and antagonists for human protease activated receptor 2.

Barry GD, Suen JY, Le GT, Cotterell A, Reid RC, Fairlie DP. Barry GD, et al. Among authors: suen jy. J Med Chem. 2010 Oct 28;53(20):7428-40. doi: 10.1021/jm100984y. J Med Chem. 2010. PMID: 20873792

4

Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells.

Suen JY, Gardiner B, Grimmond S, Fairlie DP. Suen JY, et al. PLoS One. 2010 Nov 2;5(11):e13809. doi: 10.1371/journal.pone.0013809. PLoS One. 2010. PMID: 21072196 Free PMC article.

5

Structure, function and pathophysiology of protease activated receptors.

Adams MN, Ramachandran R, Yau MK, Suen JY, Fairlie DP, Hollenberg MD, Hooper JD. Adams MN, et al. Among authors: suen jy. Pharmacol Ther. 2011 Jun;130(3):248-82. doi: 10.1016/j.pharmthera.2011.01.003. Epub 2011 Jan 26. Pharmacol Ther. 2011. PMID: 21277892 Review.

6

Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110).

Suen JY, Barry GD, Lohman RJ, Halili MA, Cotterell AJ, Le GT, Fairlie DP. Suen JY, et al. Br J Pharmacol. 2012 Mar;165(5):1413-23. doi: 10.1111/j.1476-5381.2011.01610.x. Br J Pharmacol. 2012. PMID: 21806599 Free PMC article.

7

Antagonism of protease-activated receptor 2 protects against experimental colitis.

Lohman RJ, Cotterell AJ, Suen J, Liu L, Do AT, Vesey DA, Fairlie DP. Lohman RJ, et al. J Pharmacol Exp Ther. 2012 Feb;340(2):256-65. doi: 10.1124/jpet.111.187062. Epub 2011 Oct 25. J Pharmacol Exp Ther. 2012. PMID: 22028393

8

An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats.

Lohman RJ, Cotterell AJ, Barry GD, Liu L, Suen JY, Vesey DA, Fairlie DP. Lohman RJ, et al. Among authors: suen jy. FASEB J. 2012 Jul;26(7):2877-87. doi: 10.1096/fj.11-201004. Epub 2012 Mar 30. FASEB J. 2012. PMID: 22467762

9

An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats.

Iyer A, Lim J, Poudyal H, Reid RC, Suen JY, Webster J, Prins JB, Whitehead JP, Fairlie DP, Brown L. Iyer A, et al. Among authors: suen jy. Diabetes. 2012 Sep;61(9):2320-9. doi: 10.2337/db11-1179. Diabetes. 2012. PMID: 22923652 Free PMC article.

10

C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling.

Lim J, Iyer A, Suen JY, Seow V, Reid RC, Brown L, Fairlie DP. Lim J, et al. Among authors: suen jy. FASEB J. 2013 Feb;27(2):822-31. doi: 10.1096/fj.12-220582. Epub 2012 Nov 1. FASEB J. 2013. PMID: 23118029

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