Griffiths R - Search Results

1

Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction.

Cechova S, Zeng Q, Billaud M, Mutchler S, Rudy CK, Straub AC, Chi L, Chan FR, Hu J, Griffiths R, Howell NL, Madsen K, Jensen BL, Palmer LA, Carey RM, Sung SS, Malakauskas SM, Isakson BE, Le TH. Cechova S, et al. Among authors: griffiths r. Circulation. 2013 Oct 15;128(16):1770-80. doi: 10.1161/CIRCULATIONAHA.113.003301. Epub 2013 Sep 18. Circulation. 2013. PMID: 24048198

2

Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system.

Crowley SD, Gurley SB, Oliverio MI, Pazmino AK, Griffiths R, Flannery PJ, Spurney RF, Kim HS, Smithies O, Le TH, Coffman TM. Crowley SD, et al. Among authors: griffiths r. J Clin Invest. 2005 Apr;115(4):1092-9. doi: 10.1172/JCI23378. J Clin Invest. 2005. PMID: 15841186 Free PMC article.

3

Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.

Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM. Gurley SB, et al. Among authors: griffiths r. J Clin Invest. 2006 Aug;116(8):2218-25. doi: 10.1172/JCI16980. Epub 2006 Jul 27. J Clin Invest. 2006. PMID: 16878172 Free PMC article.

4

Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.

Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim HS, Smithies O, Le TH, Coffman TM. Crowley SD, et al. Among authors: griffiths r. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17985-90. doi: 10.1073/pnas.0605545103. Epub 2006 Nov 7. Proc Natl Acad Sci U S A. 2006. PMID: 17090678 Free PMC article.

5

Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus.

Salzler HR, Griffiths R, Ruiz P, Chi L, Frey C, Marchuk DA, Rockman HA, Le TH. Salzler HR, et al. Among authors: griffiths r. Kidney Int. 2007 Nov;72(10):1226-32. doi: 10.1038/sj.ki.5002519. Epub 2007 Sep 12. Kidney Int. 2007. PMID: 17851470 Free PMC article.

6

Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression.

Facemire CS, Nixon AB, Griffiths R, Hurwitz H, Coffman TM. Facemire CS, et al. Among authors: griffiths r. Hypertension. 2009 Sep;54(3):652-8. doi: 10.1161/HYPERTENSIONAHA.109.129973. Epub 2009 Aug 3. Hypertension. 2009. PMID: 19652084 Free PMC article.

7

Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension.

Sparks MA, Parsons KK, Stegbauer J, Gurley SB, Vivekanandan-Giri A, Fortner CN, Snouwaert J, Raasch EW, Griffiths RC, Haystead TA, Le TH, Pennathur S, Koller B, Coffman TM. Sparks MA, et al. Hypertension. 2011 Mar;57(3):577-85. doi: 10.1161/HYPERTENSIONAHA.110.165274. Epub 2011 Jan 17. Hypertension. 2011. PMID: 21242463 Free PMC article.

8

A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension.

Zhang JD, Patel MB, Song YS, Griffiths R, Burchette J, Ruiz P, Sparks MA, Yan M, Howell DN, Gomez JA, Spurney RF, Coffman TM, Crowley SD. Zhang JD, et al. Among authors: griffiths r. Circ Res. 2012 Jun 8;110(12):1604-17. doi: 10.1161/CIRCRESAHA.111.261768. Epub 2012 Apr 24. Circ Res. 2012. PMID: 22534490 Free PMC article.

9

Tumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension.

Zhang J, Patel MB, Griffiths R, Mao A, Song YS, Karlovich NS, Sparks MA, Jin H, Wu M, Lin EE, Crowley SD. Zhang J, et al. Among authors: griffiths r. Hypertension. 2014 Dec;64(6):1275-81. doi: 10.1161/HYPERTENSIONAHA.114.03863. Epub 2014 Sep 2. Hypertension. 2014. PMID: 25185128 Free PMC article.

10

Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron.

Zhang J, Rudemiller NP, Patel MB, Karlovich NS, Wu M, McDonough AA, Griffiths R, Sparks MA, Jeffs AD, Crowley SD. Zhang J, et al. Among authors: griffiths r. Cell Metab. 2016 Feb 9;23(2):360-8. doi: 10.1016/j.cmet.2015.11.013. Epub 2015 Dec 17. Cell Metab. 2016. PMID: 26712462 Free PMC article.

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