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A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice.
Kelly SA, Bell TA, Selitsky SR, Buus RJ, Hua K, Weinstock GM, Garland T Jr, Pardo-Manuel de Villena F, Pomp D. Kelly SA, et al. Genetics. 2013 Dec;195(4):1385-95. doi: 10.1534/genetics.113.154476. Epub 2013 Sep 20. Genetics. 2013. PMID: 24056412 Free PMC article.
Identification of genomic loci regulating platelet plasminogen activator inhibitor-1 in mice.
Siebert AE, Brake MA, Verbeek SC, Johnston AJ, Morgan AP, Cleuren AC, Jurek AM, Schneider CD, Germain DM, Battistuzzi FU, Zhu G, Miller DR, Johnsen JM, Pardo-Manuel de Villena F, Rondina MT, Westrick RJ. Siebert AE, et al. Among authors: pardo manuel de villena f. J Thromb Haemost. 2023 Oct;21(10):2917-2928. doi: 10.1016/j.jtha.2023.06.018. Epub 2023 Jun 25. J Thromb Haemost. 2023. PMID: 37364776 Free PMC article.
On the subspecific origin of the laboratory mouse.
Yang H, Bell TA, Churchill GA, Pardo-Manuel de Villena F. Yang H, et al. Nat Genet. 2007 Sep;39(9):1100-7. doi: 10.1038/ng2087. Epub 2007 Jul 29. Nat Genet. 2007. PMID: 17660819
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.
Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT. Ferris MT, et al. PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28. PLoS Pathog. 2013. PMID: 23468633 Free PMC article.
A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.
Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F. Didion JP, et al. PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25679959 Free PMC article.
Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.
Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, Gooch TJ, Hansen SD, Robinson NN, Shaw GD, Spence JS, Quackenbush CR, Barrick CJ, Nonneman RJ, Kim K, Xenakis J, Xie Y, Valdar W, Lenarcic AB, Wang W, Welsh CE, Fu CP, Zhang Z, Holt J, Guo Z, Threadgill DW, Tarantino LM, Miller DR, Zou F, McMillan L, Sullivan PF, Pardo-Manuel de Villena F. Crowley JJ, et al. Nat Genet. 2015 Apr;47(4):353-60. doi: 10.1038/ng.3222. Epub 2015 Mar 2. Nat Genet. 2015. PMID: 25730764 Free PMC article.
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