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Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites.
Kozlenkov A, Roussos P, Timashpolsky A, Barbu M, Rudchenko S, Bibikova M, Klotzle B, Byne W, Lyddon R, Di Narzo AF, Hurd YL, Koonin EV, Dracheva S. Kozlenkov A, et al. Among authors: di narzo af. Nucleic Acids Res. 2014 Jan;42(1):109-27. doi: 10.1093/nar/gkt838. Epub 2013 Sep 20. Nucleic Acids Res. 2014. PMID: 24057217 Free PMC article.
Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.
Franzén O, Ermel R, Cohain A, Akers NK, Di Narzo A, Talukdar HA, Foroughi-Asl H, Giambartolomei C, Fullard JF, Sukhavasi K, Köks S, Gan LM, Giannarelli C, Kovacic JC, Betsholtz C, Losic B, Michoel T, Hao K, Roussos P, Skogsberg J, Ruusalepp A, Schadt EE, Björkegren JL. Franzén O, et al. Science. 2016 Aug 19;353(6301):827-30. doi: 10.1126/science.aad6970. Science. 2016. PMID: 27540175 Free PMC article.
A functional genomics predictive network model identifies regulators of inflammatory bowel disease.
Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE. Peters LA, et al. Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038/ng.3947. Epub 2017 Sep 11. Nat Genet. 2017. PMID: 28892060 Free PMC article.
A mechanistic framework for cardiometabolic and coronary artery diseases.
Koplev S, Seldin M, Sukhavasi K, Ermel R, Pang S, Zeng L, Bankier S, Di Narzo A, Cheng H, Meda V, Ma A, Talukdar H, Cohain A, Amadori L, Argmann C, Houten SM, Franzén O, Mocci G, Meelu OA, Ishikawa K, Whatling C, Jain A, Jain RK, Gan LM, Giannarelli C, Roussos P, Hao K, Schunkert H, Michoel T, Ruusalepp A, Schadt EE, Kovacic JC, Lusis AJ, Björkegren JLM. Koplev S, et al. Nat Cardiovasc Res. 2022 Jan;1(1):85-100. doi: 10.1038/s44161-021-00009-1. Epub 2022 Jan 12. Nat Cardiovasc Res. 2022. PMID: 36276926 Free PMC article.
Shared genetic etiology underlying Alzheimer's disease and type 2 diabetes.
Hao K, Di Narzo AF, Ho L, Luo W, Li S, Chen R, Li T, Dubner L, Pasinetti GM. Hao K, et al. Among authors: di narzo af. Mol Aspects Med. 2015 Jun-Oct;43-44:66-76. doi: 10.1016/j.mam.2015.06.006. Epub 2015 Jun 23. Mol Aspects Med. 2015. PMID: 26116273 Free PMC article. Review.
47 results