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NDS27 combines the effect of curcumin lysinate and hydroxypropyl-β-cyclodextrin to inhibit equine PKCδ and NADPH oxidase involved in the oxidative burst of neutrophils.
Derochette S, Mouithys-Mickalad A, Franck T, Collienne S, Ceusters J, Deby-Dupont G, Neven P, Serteyn D. Derochette S, et al. Among authors: neven p. FEBS Open Bio. 2014 Nov 18;4:1021-9. doi: 10.1016/j.fob.2014.11.004. eCollection 2014. FEBS Open Bio. 2014. PMID: 25493216 Free PMC article.
The soluble curcumin derivative NDS27 inhibits superoxide anion production by neutrophils and acts as substrate and reversible inhibitor of myeloperoxidase.
Franck T, Aldib I, Zouaoui Boudjeltia K, Furtmüller PG, Obinger C, Neven P, Prévost M, Soubhye J, Van Antwerpen P, Mouithys-Mickalad A, Serteyn D. Franck T, et al. Among authors: neven p. Chem Biol Interact. 2019 Jan 5;297:34-43. doi: 10.1016/j.cbi.2018.10.008. Epub 2018 Oct 18. Chem Biol Interact. 2019. PMID: 30342014 Free article.
566 results