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Steroidal cardiac Na+/K+ ATPase inhibitors exhibit strong anti-cancer potential in vitro and in prostate and lung cancer xenografts in vivo.
Dimas K, Papadopoulou N, Baskakis C, Prousis KC, Tsakos M, Alkahtani S, Honisch S, Lang F, Calogeropoulou T, Alevizopoulos K, Stournaras C. Dimas K, et al. Among authors: calogeropoulou t. Anticancer Agents Med Chem. 2014 Jun;14(5):762-70. doi: 10.2174/18715206113136660338. Anticancer Agents Med Chem. 2014. PMID: 24066843
Valorizing Constituents of Cashew Nut Shell Liquid toward the Sustainable Development of New Drugs against Chagas Disease.
Nunes Lemes LF, Magoulas GE, Souza de Oliveira A, Barrias E, de Camargo Nascente L, Granado R, Teixeira de Macedo Silva S, Assimomytis N, de Souza W, Bolognesi ML, Romeiro LAS, Calogeropoulou T. Nunes Lemes LF, et al. Among authors: calogeropoulou t. ACS Infect Dis. 2023 Jul 14;9(7):1334-1345. doi: 10.1021/acsinfecdis.3c00076. Epub 2023 Jun 12. ACS Infect Dis. 2023. PMID: 37307287
A steroidal Na+/K+ ATPase inhibitor triggers pro-apoptotic signaling and induces apoptosis in prostate and lung tumor cells.
Honisch S, Alkahtani S, Kounenidakis M, Liu G, Alarifi S, Al-Yahya H, Dimas K, AlKahtane AA, Prousis KC, Al-Dahmash B, Calogeropoulou T, Alevizopoulos K, Lang F, Stournaras C. Honisch S, et al. Among authors: calogeropoulou t. Anticancer Agents Med Chem. 2014;14(8):1161-8. doi: 10.2174/1871520614666140618114418. Anticancer Agents Med Chem. 2014. PMID: 24942548
Na+/K+ ATPase inhibitors in cancer.
Alevizopoulos K, Calogeropoulou T, Lang F, Stournaras C. Alevizopoulos K, et al. Among authors: calogeropoulou t. Curr Drug Targets. 2014;15(10):988-1000. Curr Drug Targets. 2014. PMID: 25198786 Review.
Functional characterization and anti-cancer action of the clinical phase II cardiac Na+/K+ ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptor.
Alevizopoulos K, Dimas K, Papadopoulou N, Schmidt EM, Tsapara A, Alkahtani S, Honisch S, Prousis KC, Alarifi S, Calogeropoulou T, Lang F, Stournaras C. Alevizopoulos K, et al. Among authors: calogeropoulou t. Oncotarget. 2016 Apr 26;7(17):24415-28. doi: 10.18632/oncotarget.8329. Oncotarget. 2016. PMID: 27027435 Free PMC article.
73 results