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Steroidal cardiac Na+/K+ ATPase inhibitors exhibit strong anti-cancer potential in vitro and in prostate and lung cancer xenografts in vivo.
Dimas K, Papadopoulou N, Baskakis C, Prousis KC, Tsakos M, Alkahtani S, Honisch S, Lang F, Calogeropoulou T, Alevizopoulos K, Stournaras C. Dimas K, et al. Among authors: honisch s. Anticancer Agents Med Chem. 2014 Jun;14(5):762-70. doi: 10.2174/18715206113136660338. Anticancer Agents Med Chem. 2014. PMID: 24066843
Functional characterization and anti-cancer action of the clinical phase II cardiac Na+/K+ ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptor.
Alevizopoulos K, Dimas K, Papadopoulou N, Schmidt EM, Tsapara A, Alkahtani S, Honisch S, Prousis KC, Alarifi S, Calogeropoulou T, Lang F, Stournaras C. Alevizopoulos K, et al. Among authors: honisch s. Oncotarget. 2016 Apr 26;7(17):24415-28. doi: 10.18632/oncotarget.8329. Oncotarget. 2016. PMID: 27027435 Free PMC article.
Chorein addiction in VPS13A overexpressing rhabdomyosarcoma cells.
Honisch S, Yu W, Liu G, Alesutan I, Towhid ST, Tsapara A, Schleicher S, Handgretinger R, Stournaras C, Lang F. Honisch S, et al. Oncotarget. 2015 Apr 30;6(12):10309-19. doi: 10.18632/oncotarget.3582. Oncotarget. 2015. PMID: 25871399 Free PMC article.
40 results