Crosby IT - Search Results

1

Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor.

Huynh T, Valant C, Crosby IT, Sexton PM, Christopoulos A, Capuano B. Huynh T, et al. Among authors: crosby it. J Med Chem. 2013 Oct 24;56(20):8196-200. doi: 10.1021/jm401032k. Epub 2013 Oct 11. J Med Chem. 2013. PMID: 24074052

2

Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation.

McRobb FM, Crosby IT, Yuriev E, Lane JR, Capuano B. McRobb FM, et al. Among authors: crosby it. J Med Chem. 2012 Feb 23;55(4):1622-34. doi: 10.1021/jm201420s. Epub 2012 Feb 2. J Med Chem. 2012. PMID: 22243698

3

Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6-tetrahydropyridines as 5-HT₂C agonists.

Conway RJ, Valant C, Christopoulos A, Robertson AD, Capuano B, Crosby IT. Conway RJ, et al. Among authors: crosby it. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2560-4. doi: 10.1016/j.bmcl.2012.01.122. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22381048

4

Synthesis and pharmacological evaluation of M4 muscarinic receptor positive allosteric modulators derived from VU10004.

Huynh T, Valant C, Crosby IT, Sexton PM, Christopoulos A, Capuano B. Huynh T, et al. Among authors: crosby it. ACS Chem Neurosci. 2015 Jun 17;6(6):838-44. doi: 10.1021/acschemneuro.5b00035. Epub 2015 Apr 17. ACS Chem Neurosci. 2015. PMID: 25857219

5

Schizophrenia: genesis, receptorology and current therapeutics.

Capuano B, Crosby IT, Lloyd EJ. Capuano B, et al. Among authors: crosby it. Curr Med Chem. 2002 Mar;9(5):521-48. doi: 10.2174/0929867024606939. Curr Med Chem. 2002. PMID: 11945123 Review.

6

Platensimycin: a promising antimicrobial targeting fatty acid synthesis.

Manallack DT, Crosby IT, Khakham Y, Capuano B. Manallack DT, et al. Among authors: crosby it. Curr Med Chem. 2008;15(7):705-10. doi: 10.2174/092986708783885255. Curr Med Chem. 2008. PMID: 18336284 Review.

7

Schizophrenia: a systematic review of the disease state, current therapeutics and their molecular mechanisms of action.

Shin JK, Malone DT, Crosby IT, Capuano B. Shin JK, et al. Among authors: crosby it. Curr Med Chem. 2011;18(9):1380-404. doi: 10.2174/092986711795029546. Curr Med Chem. 2011. PMID: 21366526 Review.

8

Homology modeling and docking evaluation of aminergic G protein-coupled receptors.

McRobb FM, Capuano B, Crosby IT, Chalmers DK, Yuriev E. McRobb FM, et al. Among authors: crosby it. J Chem Inf Model. 2010 Apr 26;50(4):626-37. doi: 10.1021/ci900444q. J Chem Inf Model. 2010. PMID: 20187660

9

N-piperonyl analogue of the atypical antipsychotic clozapine.

Capuano B, Crosby IT, Gable RW, Lloyd EJ. Capuano B, et al. Among authors: crosby it. Acta Crystallogr C. 2000 Mar;56 ( Pt 3):339-40. doi: 10.1107/S0108270199015139. Epub 2000 Mar 15. Acta Crystallogr C. 2000. PMID: 10777942 No abstract available.

10

JL13 has clozapine-like actions on thermoregulatory cutaneous blood flow in rats: Involvement of serotonin 5-HT1A and 5-HT2A receptor mechanisms.

Capuano B, Crosby IT, McRobb FM, Taylor DA, Vom A, Blessing WW. Capuano B, et al. Among authors: crosby it. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Feb 1;34(1):136-42. doi: 10.1016/j.pnpbp.2009.10.014. Epub 2009 Oct 29. Prog Neuropsychopharmacol Biol Psychiatry. 2010. PMID: 19878703

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