Loeb LA - Search Results

1

Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis.

Salk JJ, Bansal A, Lai LA, Crispin DA, Ussakli CH, Horwitz MS, Bronner MP, Brentnall TA, Loeb LA, Rabinovitch PS, Risques RA. Salk JJ, et al. Among authors: loeb la. Inflamm Bowel Dis. 2013 Nov;19(12):2593-602. doi: 10.1097/MIB.0b013e3182a87640. Inflamm Bowel Dis. 2013. PMID: 24097228 Free PMC article.

2

Clonal expansions in ulcerative colitis identify patients with neoplasia.

Salk JJ, Salipante SJ, Risques RA, Crispin DA, Li L, Bronner MP, Brentnall TA, Rabinovitch PS, Horwitz MS, Loeb LA. Salk JJ, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20871-6. doi: 10.1073/pnas.0909428106. Epub 2009 Nov 19. Proc Natl Acad Sci U S A. 2009. PMID: 19926851 Free PMC article.

3

PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.

Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA. Zhang Y, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2023373118. doi: 10.1073/pnas.2023373118. Proc Natl Acad Sci U S A. 2021. PMID: 34330826 Free PMC article.

4

Cancer genome sequencing--an interim analysis.

Fox EJ, Salk JJ, Loeb LA. Fox EJ, et al. Among authors: loeb la. Cancer Res. 2009 Jun 15;69(12):4948-50. doi: 10.1158/0008-5472.CAN-09-1231. Epub 2009 Jun 9. Cancer Res. 2009. PMID: 19509220 Free PMC article.

5

Mutational heterogeneity in human cancers: origin and consequences.

Salk JJ, Fox EJ, Loeb LA. Salk JJ, et al. Among authors: loeb la. Annu Rev Pathol. 2010;5:51-75. doi: 10.1146/annurev-pathol-121808-102113. Annu Rev Pathol. 2010. PMID: 19743960 Free PMC article. Review.

6

Frequency and spectrum of c-Ki-ras mutations in human sporadic colon carcinoma, carcinomas arising in ulcerative colitis, and pancreatic adenocarcinoma.

Burmer GC, Rabinovitch PS, Loeb LA. Burmer GC, et al. Among authors: loeb la. Environ Health Perspect. 1991 Jun;93:27-31. doi: 10.1289/ehp.919327. Environ Health Perspect. 1991. PMID: 1773797 Free PMC article.

7

The influence of subclonal resistance mutations on targeted cancer therapy.

Schmitt MW, Loeb LA, Salk JJ. Schmitt MW, et al. Among authors: loeb la. Nat Rev Clin Oncol. 2016 Jun;13(6):335-47. doi: 10.1038/nrclinonc.2015.175. Epub 2015 Oct 20. Nat Rev Clin Oncol. 2016. PMID: 26483300 Free PMC article. Review.

8

Exploring the implications of distinct mutational signatures and mutation rates in aging and cancer.

Fox EJ, Salk JJ, Loeb LA. Fox EJ, et al. Among authors: loeb la. Genome Med. 2016 Mar 17;8(1):30. doi: 10.1186/s13073-016-0286-z. Genome Med. 2016. PMID: 26987311 Free PMC article.

9

Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations.

Salk JJ, Schmitt MW, Loeb LA. Salk JJ, et al. Among authors: loeb la. Nat Rev Genet. 2018 May;19(5):269-285. doi: 10.1038/nrg.2017.117. Epub 2018 Mar 26. Nat Rev Genet. 2018. PMID: 29576615 Free PMC article. Review.

10

Optimization of DNA polymerase mutation rates during bacterial evolution.

Loh E, Salk JJ, Loeb LA. Loh E, et al. Among authors: loeb la. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1154-9. doi: 10.1073/pnas.0912451107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080608 Free PMC article.

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