Cancelas JA - Search Results

1

RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors.

Zhou X, Florian MC, Arumugam P, Chen X, Cancelas JA, Lang R, Malik P, Geiger H, Zheng Y. Zhou X, et al. Among authors: cancelas ja. J Exp Med. 2013 Oct 21;210(11):2371-85. doi: 10.1084/jem.20122348. Epub 2013 Oct 7. J Exp Med. 2013. PMID: 24101377 Free PMC article.

2

Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure.

Jansen M, Yang FC, Cancelas JA, Bailey JR, Williams DA. Jansen M, et al. Among authors: cancelas ja. Stem Cells. 2005 Mar;23(3):335-46. doi: 10.1634/stemcells.2004-0216. Stem Cells. 2005. PMID: 15749928

3

Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization.

Cancelas JA, Lee AW, Prabhakar R, Stringer KF, Zheng Y, Williams DA. Cancelas JA, et al. Nat Med. 2005 Aug;11(8):886-91. doi: 10.1038/nm1274. Epub 2005 Jul 17. Nat Med. 2005. PMID: 16025125

4

Rational design and applications of a Rac GTPase-specific small molecule inhibitor.

Akbar H, Cancelas J, Williams DA, Zheng J, Zheng Y. Akbar H, et al. Methods Enzymol. 2006;406:554-65. doi: 10.1016/S0076-6879(06)06043-5. Methods Enzymol. 2006. PMID: 16472687

5

Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment.

Ghiaur G, Lee A, Bailey J, Cancelas JA, Zheng Y, Williams DA. Ghiaur G, et al. Among authors: cancelas ja. Blood. 2006 Sep 15;108(6):2087-94. doi: 10.1182/blood-2006-02-001560. Epub 2006 May 18. Blood. 2006. PMID: 16709932 Free article.

6

Structure-function based design of small molecule inhibitors targeting Rho family GTPases.

Nassar N, Cancelas J, Zheng J, Williams DA, Zheng Y. Nassar N, et al. Curr Top Med Chem. 2006;6(11):1109-16. doi: 10.2174/156802606777812095. Curr Top Med Chem. 2006. PMID: 16842149 Review.

7

The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization.

Cancelas JA, Jansen M, Williams DA. Cancelas JA, et al. Exp Hematol. 2006 Aug;34(8):976-85. doi: 10.1016/j.exphem.2006.03.016. Exp Hematol. 2006. PMID: 16863904 Free article. Review.

8

Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow.

Yang L, Wang L, Geiger H, Cancelas JA, Mo J, Zheng Y. Yang L, et al. Among authors: cancelas ja. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5091-6. doi: 10.1073/pnas.0610819104. Epub 2007 Mar 12. Proc Natl Acad Sci U S A. 2007. PMID: 17360364 Free PMC article.

9

Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation.

Akbar H, Kim J, Funk K, Cancelas JA, Shang X, Chen L, Johnson JF, Williams DA, Zheng Y. Akbar H, et al. Among authors: cancelas ja. J Thromb Haemost. 2007 Aug;5(8):1747-55. doi: 10.1111/j.1538-7836.2007.02646.x. J Thromb Haemost. 2007. PMID: 17663742 Free article.

10

Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis.

Yang L, Wang L, Kalfa TA, Cancelas JA, Shang X, Pushkaran S, Mo J, Williams DA, Zheng Y. Yang L, et al. Among authors: cancelas ja. Blood. 2007 Dec 1;110(12):3853-61. doi: 10.1182/blood-2007-03-079582. Epub 2007 Aug 16. Blood. 2007. PMID: 17702896 Free PMC article.

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