Malek G - Search Results

1

Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.

Hu P, Herrmann R, Bednar A, Saloupis P, Dwyer MA, Yang P, Qi X, Thomas RS, Jaffe GJ, Boulton ME, McDonnell DP, Malek G. Hu P, et al. Among authors: malek g. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):E4069-78. doi: 10.1073/pnas.1307574110. Epub 2013 Oct 8. Proc Natl Acad Sci U S A. 2013. PMID: 24106308 Free PMC article.

2

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration.

Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C. Malek G, et al. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11900-5. doi: 10.1073/pnas.0503015102. Epub 2005 Aug 3. Proc Natl Acad Sci U S A. 2005. PMID: 16079201 Free PMC article.

3

Initial observations of key features of age-related macular degeneration in APOE targeted replacement mice.

Malek G, Mace B, Saloupis P, Schmechel D, Rickman D, Sullivan P, Rickman CB. Malek G, et al. Adv Exp Med Biol. 2006;572:109-17. doi: 10.1007/0-387-32442-9_17. Adv Exp Med Biol. 2006. PMID: 17249563 No abstract available.

4

Oxidative stress-induced expression and modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in mammalian retina.

Yu L, Kelly U, Ebright JN, Malek G, Saloupis P, Rickman DW, McKay BS, Arshavsky VY, Bowes Rickman C. Yu L, et al. Among authors: malek g. Biochim Biophys Acta. 2007 Sep;1773(9):1473-82. doi: 10.1016/j.bbamcr.2007.06.005. Epub 2007 Jun 26. Biochim Biophys Acta. 2007. PMID: 17673310 Free PMC article.

5

PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration.

Malek G, Hu P, Wielgus A, Dwyer M, Cousins S. Malek G, et al. Adv Exp Med Biol. 2010;664:429-36. doi: 10.1007/978-1-4419-1399-9_49. Adv Exp Med Biol. 2010. PMID: 20238044

6

Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration.

Dwyer MA, Kazmin D, Hu P, McDonnell DP, Malek G. Dwyer MA, et al. Among authors: malek g. Mol Endocrinol. 2011 Feb;25(2):360-72. doi: 10.1210/me.2010-0392. Epub 2011 Jan 14. Mol Endocrinol. 2011. PMID: 21239617 Free PMC article.

7

Exploring the potential role of the oxidant-activated transcription factor aryl hydrocarbon receptor in the pathogenesis of AMD.

Malek G, Dwyer M, McDonnell D. Malek G, et al. Adv Exp Med Biol. 2012;723:51-9. doi: 10.1007/978-1-4614-0631-0_8. Adv Exp Med Biol. 2012. PMID: 22183315 Review. No abstract available.

8

Bone marrow transplantation transfers age-related susceptibility to neovascular remodeling in murine laser-induced choroidal neovascularization.

Espinosa-Heidmann DG, Malek G, Mettu PS, Caicedo A, Saloupis P, Gach S, Dunnon AK, Hu P, Spiga MG, Cousins SW. Espinosa-Heidmann DG, et al. Among authors: malek g. Invest Ophthalmol Vis Sci. 2013 Nov 13;54(12):7439-49. doi: 10.1167/iovs.13-12546. Invest Ophthalmol Vis Sci. 2013. PMID: 24135751 Free PMC article.

9

Nuclear receptors as potential therapeutic targets for age-related macular degeneration.

Malek G. Malek G. Adv Exp Med Biol. 2014;801:317-21. doi: 10.1007/978-1-4614-3209-8_40. Adv Exp Med Biol. 2014. PMID: 24664713

10

Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration.

Malek G, Lad EM. Malek G, et al. Cell Mol Life Sci. 2014 Dec;71(23):4617-36. doi: 10.1007/s00018-014-1709-x. Epub 2014 Aug 26. Cell Mol Life Sci. 2014. PMID: 25156067 Free PMC article. Review.

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