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Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists.
Pryce G, Visintin C, Ramagopalan SV, Al-Izki S, De Faveri LE, Nuamah RA, Mein CA, Montpetit A, Hardcastle AJ, Kooij G, de Vries HE, Amor S, Thomas SA, Ledent C, Marsicano G, Lutz B, Thompson AJ, Selwood DL, Giovannoni G, Baker D. Pryce G, et al. FASEB J. 2014 Jan;28(1):117-30. doi: 10.1096/fj.13-239442. Epub 2013 Oct 11. FASEB J. 2014. PMID: 24121462
Endocannabinoids control spasticity in a multiple sclerosis model.
Baker D, Pryce G, Croxford JL, Brown P, Pertwee RG, Makriyannis A, Khanolkar A, Layward L, Fezza F, Bisogno T, Di Marzo V. Baker D, et al. Among authors: pryce g. FASEB J. 2001 Feb;15(2):300-2. doi: 10.1096/fj.00-0399fje. Epub 2000 Dec 8. FASEB J. 2001. PMID: 11156943
Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors.
Brooks JW, Pryce G, Bisogno T, Jaggar SI, Hankey DJ, Brown P, Bridges D, Ledent C, Bifulco M, Rice AS, Di Marzo V, Baker D. Brooks JW, et al. Among authors: pryce g. Eur J Pharmacol. 2002 Mar 29;439(1-3):83-92. doi: 10.1016/s0014-2999(02)01369-9. Eur J Pharmacol. 2002. PMID: 11937096
Inhibition of Rho GTPases with protein prenyltransferase inhibitors prevents leukocyte recruitment to the central nervous system and attenuates clinical signs of disease in an animal model of multiple sclerosis.
Walters CE, Pryce G, Hankey DJR, Sebti SM, Hamilton AD, Baker D, Greenwood J, Adamson P. Walters CE, et al. Among authors: pryce g. J Immunol. 2002 Apr 15;168(8):4087-4094. doi: 10.4049/jimmunol.168.8.4087. J Immunol. 2002. PMID: 11937568 Free PMC article.
The therapeutic potential of cannabis.
Baker D, Pryce G, Giovannoni G, Thompson AJ. Baker D, et al. Among authors: pryce g. Lancet Neurol. 2003 May;2(5):291-8. doi: 10.1016/s1474-4422(03)00381-8. Lancet Neurol. 2003. PMID: 12849183 Review.
109 results