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Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.
Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldovan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Ježek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR. Li M, et al. Among authors: zhang q, zhang h. Circulation. 2016 Oct 11;134(15):1105-1121. doi: 10.1161/CIRCULATIONAHA.116.023171. Epub 2016 Aug 25. Circulation. 2016. PMID: 27562971 Free PMC article.
Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.
Caruso P, Dunmore BJ, Schlosser K, Schoors S, Dos Santos C, Perez-Iratxeta C, Lavoie JR, Zhang H, Long L, Flockton AR, Frid MG, Upton PD, D'Alessandro A, Hadinnapola C, Kiskin FN, Taha M, Hurst LA, Ormiston ML, Hata A, Stenmark KR, Carmeliet P, Stewart DJ, Morrell NW. Caruso P, et al. Among authors: zhang h. Circulation. 2017 Dec 19;136(25):2451-2467. doi: 10.1161/CIRCULATIONAHA.117.028034. Epub 2017 Sep 26. Circulation. 2017. PMID: 28971999 Free PMC article.
Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton A, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Ježek P, Morrell NW, Hu CJ, Stenmark KR. Zhang H, et al. Circulation. 2017 Dec 19;136(25):2468-2485. doi: 10.1161/CIRCULATIONAHA.117.028069. Epub 2017 Sep 26. Circulation. 2017. PMID: 28972001 Free PMC article.
Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.
Li M, Riddle S, Kumar S, Poczobutt J, McKeon BA, Frid MG, Ostaff M, Reisz JA, Nemkov T, Fini MA, Laux A, Hu CJ, El Kasmi KC, D'Alessandro A, Brown RD, Zhang H, Stenmark KR. Li M, et al. Among authors: zhang h. Front Immunol. 2021 Mar 31;12:640718. doi: 10.3389/fimmu.2021.640718. eCollection 2021. Front Immunol. 2021. PMID: 33868271 Free PMC article.
Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'Alessandro A, El Kasmi KC, Ježek P, Stenmark KR. Plecitá-Hlavatá L, et al. Among authors: zhang h. Am J Respir Cell Mol Biol. 2016 Jul;55(1):47-57. doi: 10.1165/rcmb.2015-0142OC. Am J Respir Cell Mol Biol. 2016. PMID: 26699943 Free PMC article.
Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KR. Frid MG, et al. Among authors: zhang h. Am J Respir Crit Care Med. 2020 Jan 15;201(2):224-239. doi: 10.1164/rccm.201903-0591OC. Am J Respir Crit Care Med. 2020. PMID: 31545648 Free PMC article.
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