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Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design.
Prutsky GJ, Domecq JP, Erwin PJ, Briel M, Montori VM, Akl EA, Meerpohl JJ, Bassler D, Schandelmaier S, Walter SD, Zhou Q, Coello PA, Moja L, Walter M, Thorlund K, Glasziou P, Kunz R, Ferreira-Gonzalez I, Busse J, Sun X, Kristiansen A, Kasenda B, Qasim-Agha O, Pagano G, Pardo-Hernandez H, Urrutia G, Murad MH, Guyatt G. Prutsky GJ, et al. Trials. 2013 Oct 16;14:335. doi: 10.1186/1745-6215-14-335. Trials. 2013. PMID: 24131702 Free PMC article. Review.
Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit.
Murad MH, Guyatt GH, Domecq JP, Vernooij RWM, Erwin PJ, Meerpohl JJ, Prutsky GJ, Akl EA, Mueller K, Bassler D, Schandelmaier S, Walter SD, Busse JW, Kasenda B, Pagano G, Pardo-Hernandez H, Montori VM, Wang Z, Briel M. Murad MH, et al. J Clin Epidemiol. 2017 Feb;82:12-19. doi: 10.1016/j.jclinepi.2016.10.006. Epub 2016 Nov 8. J Clin Epidemiol. 2017. PMID: 27832953 Free article. Review.
GRADE Guidelines: 19. Assessing the certainty of evidence in the importance of outcomes or values and preferences-Risk of bias and indirectness.
Zhang Y, Alonso-Coello P, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Schünemann HJ. Zhang Y, et al. J Clin Epidemiol. 2019 Jul;111:94-104. doi: 10.1016/j.jclinepi.2018.01.013. Epub 2018 Feb 13. J Clin Epidemiol. 2019. PMID: 29452223
GRADE guidelines: 20. Assessing the certainty of evidence in the importance of outcomes or values and preferences-inconsistency, imprecision, and other domains.
Zhang Y, Coello PA, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Xie F, Schünemann HJ. Zhang Y, et al. J Clin Epidemiol. 2019 Jul;111:83-93. doi: 10.1016/j.jclinepi.2018.05.011. Epub 2018 May 22. J Clin Epidemiol. 2019. PMID: 29800687
Developing trustworthy recommendations as part of an urgent response (1-2 weeks): a GRADE concept paper.
Akl EA, Morgan RL, Rooney AA, Beverly B, Katikireddi SV, Agarwal A, Alper BS, Alva-Diaz C, Amato L, Ansari MT, Brozek J, Chu DK, Dahm P, Darzi AJ, Falavigna M, Gartlehner G, Pardo-Hernandez H, King V, Klugarová J, Langendam MWM, Lockwood C, Mammen M, Mathioudakis AG, McCaul M, Meerpohl JJ, Minozzi S, Mustafa RA, Nonino F, Piggott T, Qaseem A, Riva J, Rodin R, Sekercioglu N, Skoetz N, Traversy G, Thayer K, Schünemann H. Akl EA, et al. J Clin Epidemiol. 2021 Jan;129:1-11. doi: 10.1016/j.jclinepi.2020.09.037. Epub 2020 Sep 30. J Clin Epidemiol. 2021. PMID: 33010401 Free PMC article.
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