Rabe B - Search Results

1

Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.

Schwarz J, Broder C, Helmstetter A, Schmidt S, Yan I, Müller M, Schmidt-Arras D, Becker-Pauly C, Koch-Nolte F, Mittrücker HW, Rabe B, Rose-John S, Chalaris A. Schwarz J, et al. Among authors: rabe b. Biochim Biophys Acta. 2013 Dec;1833(12):3355-3367. doi: 10.1016/j.bbamcr.2013.10.005. Epub 2013 Oct 14. Biochim Biophys Acta. 2013. PMID: 24135057 Free article.

2

Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding.

Schwarz J, Schmidt S, Will O, Koudelka T, Köhler K, Boss M, Rabe B, Tholey A, Scheller J, Schmidt-Arras D, Schwake M, Rose-John S, Chalaris A. Schwarz J, et al. Among authors: rabe b. J Biol Chem. 2014 Jan 31;289(5):3080-93. doi: 10.1074/jbc.M113.536847. Epub 2013 Dec 13. J Biol Chem. 2014. PMID: 24338472 Free PMC article.

3

ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.

Yan I, Schwarz J, Lücke K, Schumacher N, Schumacher V, Schmidt S, Rabe B, Saftig P, Donners M, Rose-John S, Mittrücker HW, Chalaris A. Yan I, et al. Among authors: rabe b. J Leukoc Biol. 2016 May;99(5):749-60. doi: 10.1189/jlb.3A0515-207R. Epub 2015 Nov 11. J Leukoc Biol. 2016. PMID: 26561568

4

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils.

Chalaris A, Rabe B, Paliga K, Lange H, Laskay T, Fielding CA, Jones SA, Rose-John S, Scheller J. Chalaris A, et al. Among authors: rabe b. Blood. 2007 Sep 15;110(6):1748-55. doi: 10.1182/blood-2007-01-067918. Epub 2007 Jun 13. Blood. 2007. PMID: 17567983 Free article.

5

The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.

Chalaris A, Garbers C, Rabe B, Rose-John S, Scheller J. Chalaris A, et al. Among authors: rabe b. Eur J Cell Biol. 2011 Jun-Jul;90(6-7):484-94. doi: 10.1016/j.ejcb.2010.10.007. Epub 2010 Dec 8. Eur J Cell Biol. 2011. PMID: 21145125 Review.

6

Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding.

Effenberger T, von der Heyde J, Bartsch K, Garbers C, Schulze-Osthoff K, Chalaris A, Murphy G, Rose-John S, Rabe B. Effenberger T, et al. Among authors: rabe b. FASEB J. 2014 Nov;28(11):4847-56. doi: 10.1096/fj.14-254565. Epub 2014 Jul 30. FASEB J. 2014. PMID: 25077560

7

Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.

Riethmueller S, Ehlers JC, Lokau J, Düsterhöft S, Knittler K, Dombrowsky G, Grötzinger J, Rabe B, Rose-John S, Garbers C. Riethmueller S, et al. Among authors: rabe b. Sci Rep. 2016 May 6;6:25550. doi: 10.1038/srep25550. Sci Rep. 2016. PMID: 27151651 Free PMC article.

8

Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.

Schumacher N, Schmidt S, Schwarz J, Dohr D, Lokau J, Scheller J, Garbers C, Chalaris A, Rose-John S, Rabe B. Schumacher N, et al. Among authors: rabe b. J Immunol. 2016 Nov 1;197(9):3705-3715. doi: 10.4049/jimmunol.1600909. Epub 2016 Oct 3. J Immunol. 2016. PMID: 27698010

9

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.

Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J. Rabe B, et al. Blood. 2008 Feb 1;111(3):1021-8. doi: 10.1182/blood-2007-07-102137. Epub 2007 Nov 7. Blood. 2008. PMID: 17989316 Free article.

10

Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.

Tenhumberg S, Waetzig GH, Chalaris A, Rabe B, Seegert D, Scheller J, Rose-John S, Grötzinger J. Tenhumberg S, et al. Among authors: rabe b. J Biol Chem. 2008 Oct 3;283(40):27200-7. doi: 10.1074/jbc.M803694200. Epub 2008 Jul 23. J Biol Chem. 2008. PMID: 18650419 Free article.

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