Elseginy SA - Search Results

1

Synthesis, cytotoxic evaluation and molecular docking study of novel quinazoline derivatives as PARP-1 inhibitors.

Amin KM, Anwar MM, Kamel MM, Kassem EM, Syam YM, Elseginy SA. Amin KM, et al. Among authors: elseginy sa. Acta Pol Pharm. 2013 Sep-Oct;70(5):833-49. Acta Pol Pharm. 2013. PMID: 24147361 Free article.

2

Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran-pyrazole derivatives as anticancer agents.

Abd El-Karim SS, Anwar MM, Mohamed NA, Nasr T, Elseginy SA. Abd El-Karim SS, et al. Among authors: elseginy sa. Bioorg Chem. 2015 Dec;63:1-12. doi: 10.1016/j.bioorg.2015.08.006. Epub 2015 Aug 28. Bioorg Chem. 2015. PMID: 26368040

3

New Coumarin Derivatives as Anti-Breast and Anti-Cervical Cancer Agents Targeting VEGFR-2 and p38α MAPK.

Batran RZ, Dawood DH, El-Seginy SA, Ali MM, Maher TJ, Gugnani KS, Rondon-Ortiz AN. Batran RZ, et al. Arch Pharm (Weinheim). 2017 Sep;350(9). doi: 10.1002/ardp.201700064. Epub 2017 Aug 8. Arch Pharm (Weinheim). 2017. PMID: 28787092

4

Design, Synthesis and Biological Evaluation of Spiro Cyclohexane-1,2- Quinazoline Derivatives as Potent Dipeptidyl Peptidase IV Inhibitors.

Syam YM, El-Karim SSA, Nasr T, Elseginy SA, Anwar MM, Kamel MM, Ali HF. Syam YM, et al. Among authors: elseginy sa. Mini Rev Med Chem. 2019;19(3):250-269. doi: 10.2174/1389557517666170828121018. Mini Rev Med Chem. 2019. PMID: 28847268

5

Synthesis and molecular modeling of new benzimidazoles as glutathione S-transferase inhibitors and anticancer agents.

Abd El-Karim SS, Anwar MM, Zaki ER, Elseginy SA, Nofal ZM. Abd El-Karim SS, et al. Among authors: elseginy sa. Future Med Chem. 2018 Jan;10(2):157-181. doi: 10.4155/fmc-2017-0137. Epub 2017 Dec 13. Future Med Chem. 2018. PMID: 29235906

6

Development of Promising Thiopyrimidine-Based Anti-cancer and Antimicrobial Agents: Synthesis and QSAR Analysis.

Syam YM, Anwar MM, Kotb ER, Elseginy SA, Awad HM, Awad GEA. Syam YM, et al. Among authors: elseginy sa. Mini Rev Med Chem. 2019;19(15):1255-1275. doi: 10.2174/1389557518666180330110828. Mini Rev Med Chem. 2019. PMID: 29600761

7

Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.

Batran RZ, Kassem AF, Abbas EMH, Elseginy SA, Mounier MM. Batran RZ, et al. Among authors: elseginy sa. Bioorg Med Chem. 2018 Jul 23;26(12):3474-3490. doi: 10.1016/j.bmc.2018.05.022. Epub 2018 May 16. Bioorg Med Chem. 2018. PMID: 29793751

8

Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.

Mohamed TK, Batran RZ, Elseginy SA, Ali MM, Mahmoud AE. Mohamed TK, et al. Among authors: elseginy sa. Bioorg Chem. 2019 Apr;85:253-273. doi: 10.1016/j.bioorg.2018.12.040. Epub 2019 Jan 3. Bioorg Chem. 2019. PMID: 30641320

9

New 4-phenylcoumarin derivatives as potent 3C protease inhibitors: Design, synthesis, anti-HAV effect and molecular modeling.

Kassem AF, Batran RZ, Abbas EMH, Elseginy SA, Shaheen MNF, Elmahdy EM. Kassem AF, et al. Among authors: elseginy sa. Eur J Med Chem. 2019 Apr 15;168:447-460. doi: 10.1016/j.ejmech.2019.02.048. Epub 2019 Feb 16. Eur J Med Chem. 2019. PMID: 30844608

10

Design, synthesis, and computational validation of novel compounds selectively targeting HER2-expressing breast cancer.

Elseginy SA, Hamdy R, Menon V, Almehdi AM, El-Awady R, Soliman SSM. Elseginy SA, et al. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127658. doi: 10.1016/j.bmcl.2020.127658. Epub 2020 Oct 29. Bioorg Med Chem Lett. 2020. PMID: 33130288

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