West AC - Search Results

1

An intact immune system is required for the anticancer activities of histone deacetylase inhibitors.

West AC, Mattarollo SR, Shortt J, Cluse LA, Christiansen AJ, Smyth MJ, Johnstone RW. West AC, et al. Cancer Res. 2013 Dec 15;73(24):7265-76. doi: 10.1158/0008-5472.CAN-13-0890. Epub 2013 Oct 24. Cancer Res. 2013. PMID: 24158093

2

Eradication of solid tumors using histone deacetylase inhibitors combined with immune-stimulating antibodies.

Christiansen AJ, West A, Banks KM, Haynes NM, Teng MW, Smyth MJ, Johnstone RW. Christiansen AJ, et al. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4141-6. doi: 10.1073/pnas.1011037108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368108 Free PMC article.

3

Oncolytic virus and anti-4-1BB combination therapy elicits strong antitumor immunity against established cancer.

John LB, Howland LJ, Flynn JK, West AC, Devaud C, Duong CP, Stewart TJ, Westwood JA, Guo ZS, Bartlett DL, Smyth MJ, Kershaw MH, Darcy PK. John LB, et al. Among authors: west ac. Cancer Res. 2012 Apr 1;72(7):1651-60. doi: 10.1158/0008-5472.CAN-11-2788. Epub 2012 Feb 7. Cancer Res. 2012. PMID: 22315352

4

Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies.

Verbrugge I, Hagekyriakou J, Sharp LL, Galli M, West A, McLaughlin NM, Duret H, Yagita H, Johnstone RW, Smyth MJ, Haynes NM. Verbrugge I, et al. Cancer Res. 2012 Jul 1;72(13):3163-74. doi: 10.1158/0008-5472.CAN-12-0210. Epub 2012 May 8. Cancer Res. 2012. PMID: 22570253

5

The combination of histone deacetylase inhibitors with immune-stimulating antibodies has potent anti-cancer effects.

West AC, Christiansen AJ, Smyth MJ, Johnstone RW. West AC, et al. Oncoimmunology. 2012 May 1;1(3):377-379. doi: 10.4161/onci.18804. Oncoimmunology. 2012. PMID: 22737621 Free PMC article.

6

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.

Mattarollo SR, West AC, Steegh K, Duret H, Paget C, Martin B, Matthews GM, Shortt J, Chesi M, Bergsagel PL, Bots M, Zuber J, Lowe SW, Johnstone RW, Smyth MJ. Mattarollo SR, et al. Among authors: west ac. Blood. 2012 Oct 11;120(15):3019-29. doi: 10.1182/blood-2012-04-426643. Epub 2012 Aug 28. Blood. 2012. PMID: 22932803 Free PMC article.

7

New and emerging HDAC inhibitors for cancer treatment.

West AC, Johnstone RW. West AC, et al. J Clin Invest. 2014 Jan;124(1):30-9. doi: 10.1172/JCI69738. Epub 2014 Jan 2. J Clin Invest. 2014. PMID: 24382387 Free PMC article. Review.

8

The anticancer effects of HDAC inhibitors require the immune system.

West AC, Smyth MJ, Johnstone RW. West AC, et al. Oncoimmunology. 2014 Jan 1;3(1):e27414. doi: 10.4161/onci.27414. Oncoimmunology. 2014. PMID: 24701376 Free PMC article.

9

The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock.

West AC, Martin BP, Andrews DA, Hogg SJ, Banerjee A, Grigoriadis G, Johnstone RW, Shortt J. West AC, et al. Oncogenesis. 2016 Apr 4;5(4):e216. doi: 10.1038/oncsis.2016.26. Oncogenesis. 2016. PMID: 27043662 Free PMC article.

10

Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.

Deswaerte V, Nguyen P, West A, Browning AF, Yu L, Ruwanpura SM, Balic J, Livis T, Girard C, Preaudet A, Oshima H, Fung KY, Tye H, Najdovska M, Ernst M, Oshima M, Gabay C, Putoczki T, Jenkins BJ. Deswaerte V, et al. Cancer Res. 2018 Mar 1;78(5):1293-1307. doi: 10.1158/0008-5472.CAN-17-1887. Epub 2017 Dec 27. Cancer Res. 2018. PMID: 29282220

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