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SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.
Trautmann M, Sievers E, Aretz S, Kindler D, Michels S, Friedrichs N, Renner M, Kirfel J, Steiner S, Huss S, Koch A, Penzel R, Larsson O, Kawai A, Tanaka S, Sonobe H, Waha A, Schirmacher P, Mechtersheimer G, Wardelmann E, Büttner R, Hartmann W. Trautmann M, et al. Among authors: waha a. Oncogene. 2014 Oct 16;33(42):5006-16. doi: 10.1038/onc.2013.443. Epub 2013 Oct 28. Oncogene. 2014. PMID: 24166495
Elevated expression of Wnt antagonists is a common event in hepatoblastomas.
Koch A, Waha A, Hartmann W, Hrychyk A, Schüller U, Waha A, Wharton KA Jr, Fuchs SY, von Schweinitz D, Pietsch T. Koch A, et al. Among authors: waha a. Clin Cancer Res. 2005 Jun 15;11(12):4295-304. doi: 10.1158/1078-0432.CCR-04-1162. Clin Cancer Res. 2005. PMID: 15958610
p75(NTR) induces apoptosis in medulloblastoma cells.
Küchler J, Hartmann W, Waha A, Koch A, Endl E, Wurst P, Kindler D, Mikeska T, Waha A, Goodyer CG, Büttner R, Schilling K, Pietsch T. Küchler J, et al. Among authors: waha a. Int J Cancer. 2011 Apr 15;128(8):1804-12. doi: 10.1002/ijc.25508. Int J Cancer. 2011. PMID: 20549701
159 results