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Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant.
Mosnier LO, Zampolli A, Kerschen EJ, Schuepbach RA, Banerjee Y, Fernández JA, Yang XV, Riewald M, Weiler H, Ruggeri ZM, Griffin JH. Mosnier LO, et al. Among authors: ruggeri zm. Blood. 2009 Jun 4;113(23):5970-8. doi: 10.1182/blood-2008-10-183327. Epub 2009 Feb 24. Blood. 2009. PMID: 19244160 Free PMC article.
Neutrophils release brakes of coagulation.
Ruf W, Ruggeri ZM. Ruf W, et al. Among authors: ruggeri zm. Nat Med. 2010 Aug;16(8):851-2. doi: 10.1038/nm0810-851. Nat Med. 2010. PMID: 20689544 No abstract available.
Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Zarpellon A, Celikel R, Roberts JR, McClintock RA, Mendolicchio GL, Moore KL, Jing H, Varughese KI, Ruggeri ZM. Zarpellon A, et al. Among authors: ruggeri zm. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8628-33. doi: 10.1073/pnas.1017042108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555542 Free PMC article.
Type I interferon is a therapeutic target for virus-induced lethal vascular damage.
Baccala R, Welch MJ, Gonzalez-Quintial R, Walsh KB, Teijaro JR, Nguyen A, Ng CT, Sullivan BM, Zarpellon A, Ruggeri ZM, de la Torre JC, Theofilopoulos AN, Oldstone MB. Baccala R, et al. Among authors: ruggeri zm. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8925-30. doi: 10.1073/pnas.1408148111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889626 Free PMC article.
319 results