Pear WS - Search Results

1

T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.

De Obaldia ME, Bell JJ, Wang X, Harly C, Yashiro-Ohtani Y, DeLong JH, Zlotoff DA, Sultana DA, Pear WS, Bhandoola A. De Obaldia ME, et al. Among authors: pear ws. Nat Immunol. 2013 Dec;14(12):1277-84. doi: 10.1038/ni.2760. Epub 2013 Nov 3. Nat Immunol. 2013. PMID: 24185616 Free PMC article.

2

Notch signaling controls the generation and differentiation of early T lineage progenitors.

Sambandam A, Maillard I, Zediak VP, Xu L, Gerstein RM, Aster JC, Pear WS, Bhandoola A. Sambandam A, et al. Among authors: pear ws. Nat Immunol. 2005 Jul;6(7):663-70. doi: 10.1038/ni1216. Epub 2005 Jun 12. Nat Immunol. 2005. PMID: 15951813

3

Notch regulation of early thymocyte development.

Yashiro-Ohtani Y, Ohtani T, Pear WS. Yashiro-Ohtani Y, et al. Among authors: pear ws. Semin Immunol. 2010 Oct;22(5):261-9. doi: 10.1016/j.smim.2010.04.015. Epub 2010 Jul 13. Semin Immunol. 2010. PMID: 20630772 Review.

4

Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation.

Maillard I, Schwarz BA, Sambandam A, Fang T, Shestova O, Xu L, Bhandoola A, Pear WS. Maillard I, et al. Among authors: pear ws. Blood. 2006 May 1;107(9):3511-9. doi: 10.1182/blood-2005-08-3454. Epub 2006 Jan 5. Blood. 2006. PMID: 16397133 Free PMC article.

5

The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

Maillard I, Tu L, Sambandam A, Yashiro-Ohtani Y, Millholland J, Keeshan K, Shestova O, Xu L, Bhandoola A, Pear WS. Maillard I, et al. Among authors: pear ws. J Exp Med. 2006 Oct 2;203(10):2239-45. doi: 10.1084/jem.20061020. Epub 2006 Sep 11. J Exp Med. 2006. PMID: 16966428 Free PMC article.

6

Notch directly regulates Gata3 expression during T helper 2 cell differentiation.

Fang TC, Yashiro-Ohtani Y, Del Bianco C, Knoblock DM, Blacklow SC, Pear WS. Fang TC, et al. Among authors: pear ws. Immunity. 2007 Jul;27(1):100-10. doi: 10.1016/j.immuni.2007.04.018. Epub 2007 Jul 19. Immunity. 2007. PMID: 17658278 Free PMC article.

7

Notch dimerization is required for leukemogenesis and T-cell development.

Liu H, Chi AW, Arnett KL, Chiang MY, Xu L, Shestova O, Wang H, Li YM, Bhandoola A, Aster JC, Blacklow SC, Pear WS. Liu H, et al. Among authors: pear ws. Genes Dev. 2010 Nov 1;24(21):2395-407. doi: 10.1101/gad.1975210. Epub 2010 Oct 8. Genes Dev. 2010. PMID: 20935071 Free PMC article.

8

T cell factor 1 is required for group 2 innate lymphoid cell generation.

Yang Q, Monticelli LA, Saenz SA, Chi AW, Sonnenberg GF, Tang J, De Obaldia ME, Bailis W, Bryson JL, Toscano K, Huang J, Haczku A, Pear WS, Artis D, Bhandoola A. Yang Q, et al. Among authors: pear ws. Immunity. 2013 Apr 18;38(4):694-704. doi: 10.1016/j.immuni.2012.12.003. Immunity. 2013. PMID: 23601684 Free PMC article.

9

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

Bailis W, Yashiro-Ohtani Y, Fang TC, Hatton RD, Weaver CT, Artis D, Pear WS. Bailis W, et al. Among authors: pear ws. Immunity. 2013 Jul 25;39(1):148-59. doi: 10.1016/j.immuni.2013.07.006. Immunity. 2013. PMID: 23890069 Free PMC article.

10

Identifying direct Notch transcriptional targets using the GSI-washout assay.

Bailis W, Yashiro-Ohtani Y, Pear WS. Bailis W, et al. Among authors: pear ws. Methods Mol Biol. 2014;1187:247-54. doi: 10.1007/978-1-4939-1139-4_19. Methods Mol Biol. 2014. PMID: 25053495 Review.

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