Fallon JK - Search Results

1

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

Higgins JW, Bao JQ, Ke AB, Manro JR, Fallon JK, Smith PC, Zamek-Gliszczynski MJ. Higgins JW, et al. Among authors: fallon jk. Drug Metab Dispos. 2014 Jan;42(1):182-92. doi: 10.1124/dmd.113.054783. Epub 2013 Nov 5. Drug Metab Dispos. 2014. PMID: 24194513

2

Absolute quantification of human uridine-diphosphate glucuronosyl transferase (UGT) enzyme isoforms 1A1 and 1A6 by tandem LC-MS.

Fallon JK, Harbourt DE, Maleki SH, Kessler FK, Ritter JK, Smith PC. Fallon JK, et al. Drug Metab Lett. 2008 Aug;2(3):210-22. doi: 10.2174/187231208785425764. Drug Metab Lett. 2008. PMID: 19356096

3

Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.

Harbourt DE, Fallon JK, Ito S, Baba T, Ritter JK, Glish GL, Smith PC. Harbourt DE, et al. Among authors: fallon jk. Anal Chem. 2012 Jan 3;84(1):98-105. doi: 10.1021/ac201704a. Epub 2011 Dec 5. Anal Chem. 2012. PMID: 22050083 Free PMC article.

4

Targeted quantitative proteomics for the analysis of 14 UGT1As and -2Bs in human liver using NanoUPLC-MS/MS with selected reaction monitoring.

Fallon JK, Neubert H, Hyland R, Goosen TC, Smith PC. Fallon JK, et al. J Proteome Res. 2013 Oct 4;12(10):4402-13. doi: 10.1021/pr4004213. Epub 2013 Sep 26. J Proteome Res. 2013. PMID: 23977844

5

Targeted precise quantification of 12 human recombinant uridine-diphosphate glucuronosyl transferase 1A and 2B isoforms using nano-ultra-high-performance liquid chromatography/tandem mass spectrometry with selected reaction monitoring.

Fallon JK, Neubert H, Goosen TC, Smith PC. Fallon JK, et al. Drug Metab Dispos. 2013 Dec;41(12):2076-80. doi: 10.1124/dmd.113.053801. Epub 2013 Sep 17. Drug Metab Dispos. 2013. PMID: 24046331 Free PMC article.

6

Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues.

Margaillan G, Rouleau M, Fallon JK, Caron P, Villeneuve L, Turcotte V, Smith PC, Joy MS, Guillemette C. Margaillan G, et al. Among authors: fallon jk. Drug Metab Dispos. 2015 Apr;43(4):611-9. doi: 10.1124/dmd.114.062877. Epub 2015 Feb 3. Drug Metab Dispos. 2015. PMID: 25650382 Free PMC article.

7

Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential.

Margaillan G, Rouleau M, Klein K, Fallon JK, Caron P, Villeneuve L, Smith PC, Zanger UM, Guillemette C. Margaillan G, et al. Among authors: fallon jk. Drug Metab Dispos. 2015 Sep;43(9):1331-5. doi: 10.1124/dmd.115.065391. Epub 2015 Jun 15. Drug Metab Dispos. 2015. PMID: 26076694 Free PMC article.

8

Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.

Knights KM, Spencer SM, Fallon JK, Chau N, Smith PC, Miners JO. Knights KM, et al. Among authors: fallon jk. Br J Clin Pharmacol. 2016 Jun;81(6):1153-64. doi: 10.1111/bcp.12889. Epub 2016 Mar 14. Br J Clin Pharmacol. 2016. PMID: 26808419 Free PMC article.

9

UGT concentrations in human rectal tissue after multidose, oral curcumin.

Asher GN, Fallon JK, Smith PC. Asher GN, et al. Among authors: fallon jk. Pharmacol Res Perspect. 2016 Feb 23;4(2):e00222. doi: 10.1002/prp2.222. eCollection 2016 Apr. Pharmacol Res Perspect. 2016. PMID: 27069633 Free PMC article.

10

Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.

Fallon JK, Smith PC, Xia CQ, Kim MS. Fallon JK, et al. Pharm Res. 2016 Sep;33(9):2280-8. doi: 10.1007/s11095-016-1966-5. Epub 2016 Jun 29. Pharm Res. 2016. PMID: 27356525

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