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Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor.
Bock A, Chirinda B, Krebs F, Messerer R, Bätz J, Muth M, Dallanoce C, Klingenthal D, Tränkle C, Hoffmann C, De Amici M, Holzgrabe U, Kostenis E, Mohr K. Bock A, et al. Among authors: hoffmann c. Nat Chem Biol. 2014 Jan;10(1):18-20. doi: 10.1038/nchembio.1384. Epub 2013 Nov 10. Nat Chem Biol. 2014. PMID: 24212135
Dynamics of receptor/G protein coupling in living cells.
Hein P, Frank M, Hoffmann C, Lohse MJ, Bünemann M. Hein P, et al. Among authors: hoffmann c. EMBO J. 2005 Dec 7;24(23):4106-14. doi: 10.1038/sj.emboj.7600870. Epub 2005 Nov 17. EMBO J. 2005. PMID: 16292347 Free PMC article.
Kinetics of G-protein-coupled receptor signals in intact cells.
Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Lohse MJ, et al. Among authors: hoffmann c. Br J Pharmacol. 2008 Mar;153 Suppl 1(Suppl 1):S125-32. doi: 10.1038/sj.bjp.0707656. Epub 2008 Jan 14. Br J Pharmacol. 2008. PMID: 18193071 Free PMC article. Review.
1,631 results