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No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.
Goris A, van Setten J, Diekstra F, Ripke S, Patsopoulos NA, Sawcer SJ; International Multiple Sclerosis Genetics Consortium; van Es M; Australia and New Zealand MS Genetics Consortium; Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH Jr, Shatunov A, Leigh N, Al-Chalabi A, Shaw CE, Traynor BJ, Chiò A, Restagno G, Mora G, Ophoff RA, Oksenberg JR, Van Damme P, Compston A, Robberecht W, Dubois B, van den Berg LH, De Jager PL, Veldink JH, de Bakker PI. Goris A, et al. Among authors: van setten j, van es m, van damme p, van den berg lh. Hum Mol Genet. 2014 Apr 1;23(7):1916-22. doi: 10.1093/hmg/ddt574. Epub 2013 Nov 13. Hum Mol Genet. 2014. PMID: 24234648 Free PMC article.
Upregulation of HSP27 in a transgenic model of ALS.
Vleminckx V, Van Damme P, Goffin K, Delye H, Van Den Bosch L, Robberecht W. Vleminckx V, et al. Among authors: van damme p, van den bosch l. J Neuropathol Exp Neurol. 2002 Nov;61(11):968-74. doi: 10.1093/jnen/61.11.968. J Neuropathol Exp Neurol. 2002. PMID: 12430713
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.
Storkebaum E, Lambrechts D, Dewerchin M, Moreno-Murciano MP, Appelmans S, Oh H, Van Damme P, Rutten B, Man WY, De Mol M, Wyns S, Manka D, Vermeulen K, Van Den Bosch L, Mertens N, Schmitz C, Robberecht W, Conway EM, Collen D, Moons L, Carmeliet P. Storkebaum E, et al. Among authors: van damme p, van den bosch l. Nat Neurosci. 2005 Jan;8(1):85-92. doi: 10.1038/nn1360. Epub 2004 Nov 28. Nat Neurosci. 2005. PMID: 15568021 Free article.
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.
Van Damme P, Bogaert E, Dewil M, Hersmus N, Kiraly D, Scheveneels W, Bockx I, Braeken D, Verpoorten N, Verhoeven K, Timmerman V, Herijgers P, Callewaert G, Carmeliet P, Van Den Bosch L, Robberecht W. Van Damme P, et al. Among authors: van den bosch l. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14825-30. doi: 10.1073/pnas.0705046104. Epub 2007 Sep 5. Proc Natl Acad Sci U S A. 2007. PMID: 17804792 Free PMC article.
Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration.
Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, Van Den Bosch L, Meert T, D'Hooge R, Sendtner M, Robberecht W, Carmeliet P. Poesen K, et al. Among authors: van damme p, van den bosch l. J Neurosci. 2008 Oct 15;28(42):10451-9. doi: 10.1523/JNEUROSCI.1092-08.2008. J Neurosci. 2008. PMID: 18923022 Free PMC article.
VEGF protects motor neurons against excitotoxicity by upregulation of GluR2.
Bogaert E, Van Damme P, Poesen K, Dhondt J, Hersmus N, Kiraly D, Scheveneels W, Robberecht W, Van Den Bosch L. Bogaert E, et al. Among authors: van damme p, van den bosch l. Neurobiol Aging. 2010 Dec;31(12):2185-91. doi: 10.1016/j.neurobiolaging.2008.12.007. Epub 2009 Jan 29. Neurobiol Aging. 2010. PMID: 19185395
1,258 results