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Up-regulation of Egr1 by 1,25-dihydroxyvitamin D3 contributes to increased expression of p35 activator of cyclin-dependent kinase 5 and consequent onset of the terminal phase of HL60 cell differentiation.
Chen F, Wang Q, Wang X, Studzinski GP. Chen F, et al. Among authors: wang x, wang q. Cancer Res. 2004 Aug 1;64(15):5425-33. doi: 10.1158/0008-5472.CAN-04-0806. Cancer Res. 2004. PMID: 15289351
This laboratory has also provided evidence that the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is active in the early (24-48 h) stages of HL60 cell differentiation induced by 1,25D(3) but declines in the later, terminal phase of this form of di …
This laboratory has also provided evidence that the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is active …
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