Ghysdael J - Search Results

1

Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors.

Waibel M, Solomon VS, Knight DA, Ralli RA, Kim SK, Banks KM, Vidacs E, Virely C, Sia KC, Bracken LS, Collins-Underwood R, Drenberg C, Ramsey LB, Meyer SC, Takiguchi M, Dickins RA, Levine R, Ghysdael J, Dawson MA, Lock RB, Mullighan CG, Johnstone RW. Waibel M, et al. Among authors: ghysdael j. Cell Rep. 2013 Nov 27;5(4):1047-59. doi: 10.1016/j.celrep.2013.10.038. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268771 Free PMC article.

2

Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia.

Hawkins ED, Oliaro J, Ramsbottom KM, Ting SB, Sacirbegovic F, Harvey M, Kinwell T, Ghysdael J, Johnstone RW, Humbert PO, Russell SM. Hawkins ED, et al. Among authors: ghysdael j. PLoS One. 2014 Jan 27;9(1):e87376. doi: 10.1371/journal.pone.0087376. eCollection 2014. PLoS One. 2014. PMID: 24475281 Free PMC article.

3

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.

Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, Skok JA. Hewitt SL, et al. Among authors: ghysdael j. Nat Immunol. 2009 Jun;10(6):655-64. doi: 10.1038/ni.1735. Nat Immunol. 2009. PMID: 19448632 Free PMC article.

4

CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.

Passaro D, Irigoyen M, Catherinet C, Gachet S, Da Costa De Jesus C, Lasgi C, Tran Quang C, Ghysdael J. Passaro D, et al. Among authors: ghysdael j. Cancer Cell. 2015 Jun 8;27(6):769-79. doi: 10.1016/j.ccell.2015.05.003. Cancer Cell. 2015. PMID: 26058076 Free article.

5

Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia.

Medyouf H, Alcalde H, Berthier C, Guillemin MC, dos Santos NR, Janin A, Decaudin D, de Thé H, Ghysdael J. Medyouf H, et al. Among authors: ghysdael j. Nat Med. 2007 Jun;13(6):736-41. doi: 10.1038/nm1588. Epub 2007 May 21. Nat Med. 2007. PMID: 17515895

6

The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors.

Medyouf H, Ghysdael J. Medyouf H, et al. Among authors: ghysdael j. Cell Cycle. 2008 Feb 1;7(3):297-303. doi: 10.4161/cc.7.3.5357. Epub 2007 Nov 23. Cell Cycle. 2008. PMID: 18235236 Review.

7

Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia.

dos Santos NR, Rickman DS, de Reynies A, Cormier F, Williame M, Blanchard C, Stern MH, Ghysdael J. dos Santos NR, et al. Among authors: ghysdael j. Blood. 2007 May 1;109(9):3972-81. doi: 10.1182/blood-2006-09-048801. Epub 2006 Dec 27. Blood. 2007. PMID: 17192390 Free article.

8

Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia.

Gachet S, Genescà E, Passaro D, Irigoyen M, Alcalde H, Clémenson C, Poglio S, Pflumio F, Janin A, Lasgi C, Dodier S, Soyer M, Duménil G, Ghysdael J. Gachet S, et al. Among authors: ghysdael j. Leukemia. 2013 Dec;27(12):2289-300. doi: 10.1038/leu.2013.156. Epub 2013 May 21. Leukemia. 2013. PMID: 23689515

9

Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia.

Virely C, Moulin S, Cobaleda C, Lasgi C, Alberdi A, Soulier J, Sigaux F, Chan S, Kastner P, Ghysdael J. Virely C, et al. Among authors: ghysdael j. Leukemia. 2010 Jun;24(6):1200-4. doi: 10.1038/leu.2010.63. Epub 2010 Apr 15. Leukemia. 2010. PMID: 20393504 No abstract available.

10

NFAT transcription factors are essential and redundant actors for leukemia initiating potential in T-cell acute lymphoblastic leukemia.

Catherinet C, Passaro D, Gachet S, Medyouf H, Reynaud A, Lasgi C, Ghysdael J, Tran Quang C. Catherinet C, et al. Among authors: ghysdael j. PLoS One. 2021 Jul 7;16(7):e0254184. doi: 10.1371/journal.pone.0254184. eCollection 2021. PLoS One. 2021. PMID: 34234374 Free PMC article.

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