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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Tucsek Z, Toth P, Sosnowska D, Gautam T, Mitschelen M, Koller A, Szalai G, Sonntag WE, Ungvari Z, Csiszar A. Tucsek Z, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2014 Oct;69(10):1212-26. doi: 10.1093/gerona/glt177. Epub 2013 Nov 22. J Gerontol A Biol Sci Med Sci. 2014. PMID: 24269929 Free PMC article.
Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.
Ungvari Z, Sosnowska D, Podlutsky A, Koncz P, Sonntag WE, Csiszar A. Ungvari Z, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2011 May;66(5):501-10. doi: 10.1093/gerona/glr004. Epub 2011 Feb 24. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21350246 Free PMC article.
Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal.
Ungvari Z, Ridgway I, Philipp EE, Campbell CM, McQuary P, Chow T, Coelho M, Didier ES, Gelino S, Holmbeck MA, Kim I, Levy E, Sosnowska D, Sonntag WE, Austad SN, Csiszar A. Ungvari Z, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2011 Jul;66(7):741-50. doi: 10.1093/gerona/glr044. Epub 2011 Apr 12. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21486920 Free PMC article.
Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.
Ungvari Z, Bailey-Downs L, Sosnowska D, Gautam T, Koncz P, Losonczy G, Ballabh P, de Cabo R, Sonntag WE, Csiszar A. Ungvari Z, et al. Among authors: sosnowska d. Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H363-72. doi: 10.1152/ajpheart.01134.2010. Epub 2011 May 20. Am J Physiol Heart Circ Physiol. 2011. PMID: 21602469 Free PMC article.
Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.
Ungvari Z, Bailey-Downs L, Gautam T, Sosnowska D, Wang M, Monticone RE, Telljohann R, Pinto JT, de Cabo R, Sonntag WE, Lakatta EG, Csiszar A. Ungvari Z, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2011 Aug;66(8):866-75. doi: 10.1093/gerona/glr092. Epub 2011 May 28. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21622983 Free PMC article.
Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
Bailey-Downs LC, Mitschelen M, Sosnowska D, Toth P, Pinto JT, Ballabh P, Valcarcel-Ares MN, Farley J, Koller A, Henthorn JC, Bass C, Sonntag WE, Ungvari Z, Csiszar A. Bailey-Downs LC, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):313-29. doi: 10.1093/gerona/glr164. Epub 2011 Oct 21. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22021391 Free PMC article.
Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging.
Bailey-Downs LC, Sosnowska D, Toth P, Mitschelen M, Gautam T, Henthorn JC, Ballabh P, Koller A, Farley JA, Sonntag WE, Csiszar A, Ungvari Z. Bailey-Downs LC, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):553-64. doi: 10.1093/gerona/glr197. Epub 2011 Nov 10. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22080499 Free PMC article.
Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging.
Valcarcel-Ares MN, Gautam T, Warrington JP, Bailey-Downs L, Sosnowska D, de Cabo R, Losonczy G, Sonntag WE, Ungvari Z, Csiszar A. Valcarcel-Ares MN, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2012 Aug;67(8):821-9. doi: 10.1093/gerona/glr229. Epub 2012 Jan 4. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22219515 Free PMC article.
Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).
Ungvari Z, Csiszar A, Sosnowska D, Philipp EE, Campbell CM, McQuary PR, Chow TT, Coelho M, Didier ES, Gelino S, Holmbeck MA, Kim I, Levy E, Sonntag WE, Whitby PW, Austad SN, Ridgway I. Ungvari Z, et al. Among authors: sosnowska d. J Gerontol A Biol Sci Med Sci. 2013 Apr;68(4):359-67. doi: 10.1093/gerona/gls159. Epub 2012 Aug 17. J Gerontol A Biol Sci Med Sci. 2013. PMID: 22904097 Free PMC article.
91 results