Tesmer JJ - Search Results

1

Strike a pose: Gαq complexes at the membrane.

Lyon AM, Taylor VG, Tesmer JJ. Lyon AM, et al. Among authors: tesmer jj. Trends Pharmacol Sci. 2014 Jan;35(1):23-30. doi: 10.1016/j.tips.2013.10.008. Epub 2013 Nov 26. Trends Pharmacol Sci. 2014. PMID: 24287282 Free PMC article. Review.

2

Assembly of high order G alpha q-effector complexes with RGS proteins.

Shankaranarayanan A, Thal DM, Tesmer VM, Roman DL, Neubig RR, Kozasa T, Tesmer JJ. Shankaranarayanan A, et al. Among authors: tesmer jj, tesmer vm. J Biol Chem. 2008 Dec 12;283(50):34923-34. doi: 10.1074/jbc.M805860200. Epub 2008 Oct 20. J Biol Chem. 2008. PMID: 18936096 Free PMC article.

3

A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.

Aittaleb M, Gao G, Evelyn CR, Neubig RR, Tesmer JJ. Aittaleb M, et al. Among authors: tesmer jj. Cell Signal. 2009 Nov;21(11):1569-78. doi: 10.1016/j.cellsig.2009.06.003. Epub 2009 Jun 26. Cell Signal. 2009. PMID: 19560536 Free PMC article.

4

Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.

Aittaleb M, Boguth CA, Tesmer JJ. Aittaleb M, et al. Among authors: tesmer jj. Mol Pharmacol. 2010 Feb;77(2):111-25. doi: 10.1124/mol.109.061234. Epub 2009 Oct 30. Mol Pharmacol. 2010. PMID: 19880753 Free PMC article. Review.

5

Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.

Shankaranarayanan A, Boguth CA, Lutz S, Vettel C, Uhlemann F, Aittaleb M, Wieland T, Tesmer JJ. Shankaranarayanan A, et al. Among authors: tesmer jj. Cell Signal. 2010 Jul;22(7):1114-23. doi: 10.1016/j.cellsig.2010.03.006. Epub 2010 Mar 7. Cell Signal. 2010. PMID: 20214977 Free PMC article.

6

The quest to understand heterotrimeric G protein signaling.

Tesmer JJ. Tesmer JJ. Nat Struct Mol Biol. 2010 Jun;17(6):650-2. doi: 10.1038/nsmb0610-650. Nat Struct Mol Biol. 2010. PMID: 20520658 Free PMC article. Review.

7

Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs.

Huang CC, Tesmer JJG. Huang CC, et al. J Biol Chem. 2011 Mar 11;286(10):7715-7721. doi: 10.1074/jbc.R109.051847. Epub 2011 Jan 3. J Biol Chem. 2011. PMID: 21199869 Free PMC article. Review.

8

An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activation.

Lyon AM, Tesmer VM, Dhamsania VD, Thal DM, Gutierrez J, Chowdhury S, Suddala KC, Northup JK, Tesmer JJ. Lyon AM, et al. Among authors: tesmer jj, tesmer vm. Nat Struct Mol Biol. 2011 Aug 7;18(9):999-1005. doi: 10.1038/nsmb.2095. Nat Struct Mol Biol. 2011. PMID: 21822282 Free PMC article.

9

Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells.

Aittaleb M, Nishimura A, Linder ME, Tesmer JJ. Aittaleb M, et al. Among authors: tesmer jj. J Biol Chem. 2011 Sep 30;286(39):34448-56. doi: 10.1074/jbc.M111.273342. Epub 2011 Aug 10. J Biol Chem. 2011. PMID: 21832057 Free PMC article.

10

Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane.

Boughton AP, Yang P, Tesmer VM, Ding B, Tesmer JJ, Chen Z. Boughton AP, et al. Among authors: tesmer jj, tesmer vm. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):E667-73. doi: 10.1073/pnas.1108236108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876134 Free PMC article.

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