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Page 1
Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors.
Ross-Macdonald P, de Silva H, Patel V, Truong A, He A, Neuhaus I, Tilford C, Ji R, Siemers N, Greer A, Carboni J, Gottardis M, Menard K, Lee F, Dodier M, Frennesson D, Sampognaro A, Saulnier M, Trainor G, Vyas D, Zimmermann K, Wittman M. Ross-Macdonald P, et al. Bioorg Med Chem. 2012 Mar 15;20(6):1961-72. doi: 10.1016/j.bmc.2011.10.090. Epub 2011 Nov 6. Bioorg Med Chem. 2012. PMID: 22137930
Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.
Civelek M, Wu Y, Pan C, Raulerson CK, Ko A, He A, Tilford C, Saleem NK, Stančáková A, Scott LJ, Fuchsberger C, Stringham HM, Jackson AU, Narisu N, Chines PS, Small KS, Kuusisto J, Parks BW, Pajukanta P, Kirchgessner T, Collins FS, Gargalovic PS, Boehnke M, Laakso M, Mohlke KL, Lusis AJ. Civelek M, et al. Am J Hum Genet. 2017 Mar 2;100(3):428-443. doi: 10.1016/j.ajhg.2017.01.027. Am J Hum Genet. 2017. PMID: 28257690 Free PMC article.
Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution.
Wu Y, Broadaway KA, Raulerson CK, Scott LJ, Pan C, Ko A, He A, Tilford C, Fuchsberger C, Locke AE, Stringham HM, Jackson AU, Narisu N, Kuusisto J, Pajukanta P, Collins FS, Boehnke M, Laakso M, Lusis AJ, Civelek M, Mohlke KL. Wu Y, et al. Hum Mol Genet. 2019 Dec 15;28(24):4161-4172. doi: 10.1093/hmg/ddz263. Hum Mol Genet. 2019. PMID: 31691812 Free PMC article.
Systems genetics analysis of gene-by-environment interactions in human cells.
Romanoski CE, Lee S, Kim MJ, Ingram-Drake L, Plaisier CL, Yordanova R, Tilford C, Guan B, He A, Gargalovic PS, Kirchgessner TG, Berliner JA, Lusis AJ. Romanoski CE, et al. Am J Hum Genet. 2010 Mar 12;86(3):399-410. doi: 10.1016/j.ajhg.2010.02.002. Epub 2010 Feb 18. Am J Hum Genet. 2010. PMID: 20170901 Free PMC article.
Gene set enrichment analysis.
Tilford CA, Siemers NO. Tilford CA, et al. Methods Mol Biol. 2009;563:99-121. doi: 10.1007/978-1-60761-175-2_6. Methods Mol Biol. 2009. PMID: 19597782
Comparative analysis of proteome and transcriptome variation in mouse.
Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG 2nd, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ. Ghazalpour A, et al. PLoS Genet. 2011 Jun;7(6):e1001393. doi: 10.1371/journal.pgen.1001393. Epub 2011 Jun 9. PLoS Genet. 2011. PMID: 21695224 Free PMC article.
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