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Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors.
Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):355-64. doi: 10.1161/ATVBAHA.113.302854. Epub 2013 Dec 5.
Arterioscler Thromb Vasc Biol. 2014.
PMID: 24311380
Free PMC article.
Mineralocorticoid receptor antagonism inhibits vein graft remodeling in mice.
Ehsan A, McGraw AP, Aronovitz MJ, Galayda C, Conte MS, Karas RH, Jaffe IZ.
Ehsan A, et al. Among authors: galayda c.
J Thorac Cardiovasc Surg. 2013 Jun;145(6):1642-9, 1649.e1. doi: 10.1016/j.jtcvs.2012.08.007. Epub 2012 Sep 13.
J Thorac Cardiovasc Surg. 2013.
PMID: 22982037
Free PMC article.
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Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.
McGraw AP, Bagley J, Chen WS, Galayda C, Nickerson H, Armani A, Caprio M, Carmeliet P, Jaffe IZ.
McGraw AP, et al. Among authors: galayda c.
J Am Heart Assoc. 2013 Feb 22;2(1):e000018. doi: 10.1161/JAHA.112.000018.
J Am Heart Assoc. 2013.
PMID: 23525413
Free PMC article.
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