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Telaprevir twice daily is noninferior to telaprevir every 8 hours for patients with chronic hepatitis C.
Buti M, Agarwal K, Horsmans Y, Sievert W, Janczewska E, Zeuzem S, Nyberg L, Brown RS Jr, Hézode C, Rizzetto M, Paraná R, De Meyer S, De Masi R, Luo D, Bertelsen K, Witek J. Buti M, et al. Among authors: bertelsen k. Gastroenterology. 2014 Mar;146(3):744-753.e3. doi: 10.1053/j.gastro.2013.11.047. Epub 2013 Dec 4. Gastroenterology. 2014. PMID: 24316262 Free article. Clinical Trial.
Peficitinib, an Oral Janus Kinase Inhibitor, in Moderate-to-severe Ulcerative Colitis: Results From a Randomised, Phase 2 Study.
Sands BE, Sandborn WJ, Feagan BG, Lichtenstein GR, Zhang H, Strauss R, Szapary P, Johanns J, Panes J, Vermeire S, O'Brien CD, Yang Z, Bertelsen K, Marano C; Peficitinib-UC Study Group. Sands BE, et al. Among authors: bertelsen k. J Crohns Colitis. 2018 Nov 9;12(10):1158-1169. doi: 10.1093/ecco-jcc/jjy085. J Crohns Colitis. 2018. PMID: 29917064 Clinical Trial.
A brief survey of first-in-human studies.
Wexler D, Bertelsen KM. Wexler D, et al. J Clin Pharmacol. 2011 Jul;51(7):988-93. doi: 10.1177/0091270010377631. Epub 2010 Jul 29. J Clin Pharmacol. 2011. PMID: 20671293
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.
Bonaventure P, Dugovic C, Kramer M, De Boer P, Singh J, Wilson S, Bertelsen K, Di J, Shelton J, Aluisio L, Dvorak L, Fraser I, Lord B, Nepomuceno D, Ahnaou A, Drinkenburg W, Chai W, Dvorak C, Sands S, Carruthers N, Lovenberg TW. Bonaventure P, et al. Among authors: bertelsen k. J Pharmacol Exp Ther. 2012 Aug;342(2):429-40. doi: 10.1124/jpet.112.193995. Epub 2012 May 8. J Pharmacol Exp Ther. 2012. PMID: 22570363 Clinical Trial.
A highly sensitive and selective method for the determination of leukotriene B4 (LTB4) in ex vivo stimulated human plasma by ultra fast liquid chromatography-tandem mass spectrometry.
Lin W, Huang MQ, Xue X, Bertelsen K, Chen G, Zhao H, Lin ZJ, Fourie A, de Jong J, Weng N. Lin W, et al. Among authors: bertelsen k. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Apr 15;925:54-62. doi: 10.1016/j.jchromb.2013.02.038. Epub 2013 Mar 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23523878
Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.
Zhang W, Han F, Guo P, Zhao H, Lin ZJ, Huang MQ, Bertelsen K, Weng N. Zhang W, et al. Among authors: bertelsen k. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 1;878(15-16):1169-77. doi: 10.1016/j.jchromb.2010.03.026. Epub 2010 Mar 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20378422
106 results