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RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.
Bohgaki M, Bohgaki T, El Ghamrasni S, Srikumar T, Maire G, Panier S, Fradet-Turcotte A, Stewart GS, Raught B, Hakem A, Hakem R. Bohgaki M, et al. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):20982-7. doi: 10.1073/pnas.1320302111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324146 Free PMC article.
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Fradet-Turcotte A, Canny MD, Escribano-Díaz C, Orthwein A, Leung CC, Huang H, Landry MC, Kitevski-LeBlanc J, Noordermeer SM, Sicheri F, Durocher D. Fradet-Turcotte A, et al. Nature. 2013 Jul 4;499(7456):50-4. doi: 10.1038/nature12318. Epub 2013 Jun 12. Nature. 2013. PMID: 23760478 Free PMC article.
Human papillomavirus E7 oncoprotein targets RNF168 to hijack the host DNA damage response.
Sitz J, Blanchet SA, Gameiro SF, Biquand E, Morgan TM, Galloy M, Dessapt J, Lavoie EG, Blondeau A, Smith BC, Mymryk JS, Moody CA, Fradet-Turcotte A. Sitz J, et al. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19552-19562. doi: 10.1073/pnas.1906102116. Epub 2019 Sep 9. Proc Natl Acad Sci U S A. 2019. PMID: 31501315 Free PMC article.
p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH.
Di Lello P, Miller Jenkins LM, Mas C, Langlois C, Malitskaya E, Fradet-Turcotte A, Archambault J, Legault P, Omichinski JG. Di Lello P, et al. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):106-11. doi: 10.1073/pnas.0707892105. Epub 2007 Dec 26. Proc Natl Acad Sci U S A. 2008. PMID: 18160537 Free PMC article.
47 results