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RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.
Bohgaki M, Bohgaki T, El Ghamrasni S, Srikumar T, Maire G, Panier S, Fradet-Turcotte A, Stewart GS, Raught B, Hakem A, Hakem R. Bohgaki M, et al. Among authors: hakem a, hakem r. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):20982-7. doi: 10.1073/pnas.1320302111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324146 Free PMC article.
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity.
Salmena L, Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K, Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, Wakeham A, Bouchard D, Yeh WC, McGlade JC, Ohashi PS, Hakem R. Salmena L, et al. Among authors: hakem a, hakem r. Genes Dev. 2003 Apr 1;17(7):883-95. doi: 10.1101/gad.1063703. Epub 2003 Mar 21. Genes Dev. 2003. PMID: 12654726 Free PMC article.
Collaboration of Brca1 and Chk2 in tumorigenesis.
McPherson JP, Lemmers B, Hirao A, Hakem A, Abraham J, Migon E, Matysiak-Zablocki E, Tamblyn L, Sanchez-Sweatman O, Khokha R, Squire J, Hande MP, Mak TW, Hakem R. McPherson JP, et al. Among authors: hakem a, hakem r. Genes Dev. 2004 May 15;18(10):1144-53. doi: 10.1101/gad.1192704. Epub 2004 May 6. Genes Dev. 2004. PMID: 15131084 Free PMC article.
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.
McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R. McPherson JP, et al. Among authors: hakem a, hakem r. EMBO J. 2004 Sep 15;23(18):3677-88. doi: 10.1038/sj.emboj.7600371. Epub 2004 Sep 2. EMBO J. 2004. PMID: 15343267 Free PMC article.
Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling.
Lemmers B, Salmena L, Bidère N, Su H, Matysiak-Zablocki E, Murakami K, Ohashi PS, Jurisicova A, Lenardo M, Hakem R, Hakem A. Lemmers B, et al. Among authors: hakem a, hakem r. J Biol Chem. 2007 Mar 9;282(10):7416-23. doi: 10.1074/jbc.M606721200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213198 Free article.
Functional interplay of p53 and Mus81 in DNA damage responses and cancer.
Pamidi A, Cardoso R, Hakem A, Matysiak-Zablocki E, Poonepalli A, Tamblyn L, Perez-Ordonez B, Hande MP, Sanchez O, Hakem R. Pamidi A, et al. Among authors: hakem a, hakem r. Cancer Res. 2007 Sep 15;67(18):8527-35. doi: 10.1158/0008-5472.CAN-07-1161. Cancer Res. 2007. PMID: 17875692
117 results