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A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation.
Bernstock JD, Lee YJ, Peruzzotti-Jametti L, Southall N, Johnson KR, Maric D, Volpe G, Kouznetsova J, Zheng W, Pluchino S, Hallenbeck JM. Bernstock JD, et al. Among authors: pluchino s. J Cereb Blood Flow Metab. 2016 Feb;36(2):426-41. doi: 10.1177/0271678X15609939. Epub 2015 Oct 23. J Cereb Blood Flow Metab. 2016. PMID: 26661196 Free PMC article.
153 results