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Dual targeted 2-Benzylideneindanone pendant hydroxamic acid group exhibits selective HDAC6 inhibition along with tubulin stabilization effect.
Kumar K, Das R, Thapa B, Rakhecha B, Srivastava S, Savita K, Israr M, Chanda D, Banerjee D, Shanker K, Bawankule DU, Santini B, Di Paolo ML, Via LD, Passarella D, Negi AS. Kumar K, et al. Among authors: passarella d. Bioorg Med Chem. 2023 May 15;86:117300. doi: 10.1016/j.bmc.2023.117300. Epub 2023 Apr 27. Bioorg Med Chem. 2023. PMID: 37146520
Dehydroroyleanone as a Building Block for a Drug Delivery Platform Based on Self-Assembled Nanoparticles: Structural Studies and Chemical Modification.
García C, Bernardes CES, Piedade MFM, Fumagalli G, Colombo E, Díaz-Lanza AM, Reis CP, Correia I, Ascensão L, Passarella D, da Piedade MEM, Rijo P. García C, et al. Among authors: passarella d. ACS Omega. 2022 Nov 23;7(48):44180-44186. doi: 10.1021/acsomega.2c05353. eCollection 2022 Dec 6. ACS Omega. 2022. PMID: 36506152 Free PMC article.
Synthesis of SARS-CoV-2 Mpro inhibitors bearing a cinnamic ester warhead with in vitro activity against human coronaviruses.
Citarella A, Moi D, Pedrini M, Pérez-Peña H, Pieraccini S, Dimasi A, Stagno C, Micale N, Schirmeister T, Sibille G, Gribaudo G, Silvani A, Giannini C, Passarella D. Citarella A, et al. Among authors: passarella d. Org Biomol Chem. 2023 May 10;21(18):3811-3824. doi: 10.1039/d3ob00381g. Org Biomol Chem. 2023. PMID: 37078164 Free article.
132 results