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Relevant issues in the pathology and pathobiology of pulmonary hypertension.
Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. Tuder RM, et al. Among authors: guignabert c. J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D4-12. doi: 10.1016/j.jacc.2013.10.025. J Am Coll Cardiol. 2013. PMID: 24355640 Free PMC article. Review.
Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling.
El-Bizri N, Wang L, Merklinger SL, Guignabert C, Desai T, Urashima T, Sheikh AY, Knutsen RH, Mecham RP, Mishina Y, Rabinovitch M. El-Bizri N, et al. Among authors: guignabert c. Circ Res. 2008 Feb 15;102(3):380-8. doi: 10.1161/CIRCRESAHA.107.161059. Epub 2007 Dec 13. Circ Res. 2008. PMID: 18079409 Free PMC article.
S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4.
Spiekerkoetter E, Guignabert C, de Jesus Perez V, Alastalo TP, Powers JM, Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Rabinovitch M. Spiekerkoetter E, et al. Among authors: guignabert c. Circ Res. 2009 Sep 25;105(7):639-47, 13 p following 647. doi: 10.1161/CIRCRESAHA.109.205120. Epub 2009 Aug 27. Circ Res. 2009. PMID: 19713532 Free PMC article.
Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.
Guignabert C, Alvira CM, Alastalo TP, Sawada H, Hansmann G, Zhao M, Wang L, El-Bizri N, Rabinovitch M. Guignabert C, et al. Am J Physiol Lung Cell Mol Physiol. 2009 Dec;297(6):L1082-90. doi: 10.1152/ajplung.00199.2009. Epub 2009 Oct 2. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19801450 Free PMC article.
A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.
Tu L, De Man FS, Girerd B, Huertas A, Chaumais MC, Lecerf F, François C, Perros F, Dorfmüller P, Fadel E, Montani D, Eddahibi S, Humbert M, Guignabert C. Tu L, et al. Among authors: guignabert c. Am J Respir Crit Care Med. 2012 Oct 1;186(7):666-76. doi: 10.1164/rccm.201202-0309OC. Epub 2012 Jul 12. Am J Respir Crit Care Med. 2012. PMID: 22798315 Free PMC article.
176 results